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Human milk lactoferrin and lysozyme concentrations vary in response to a dietary intervention.
Sindi, Azhar S; Stinson, Lisa F; Lai, Ching Tat; Gridneva, Zoya; Leghi, Gabriela E; Netting, Merryn J; Wlodek, Mary E; Muhlhausler, Beverly S; Zhou, Xiaojie; Payne, Matthew S; Geddes, Donna T.
Afiliación
  • Sindi AS; Division of Obstetrics and Gynaecology, School of Medicine, The University of Western Australia, Subiaco, WA 6008, Australia; College of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia; ABREAST Network, Perth, WA 6000, Australia; UWA Centre for Human Lactation Research and Tra
  • Stinson LF; ABREAST Network, Perth, WA 6000, Australia; UWA Centre for Human Lactation Research and Translation, Crawley, WA 6009, Australia; School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia. Electronic address: lisa.stinson@uwa.edu.au.
  • Lai CT; ABREAST Network, Perth, WA 6000, Australia; UWA Centre for Human Lactation Research and Translation, Crawley, WA 6009, Australia; School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia. Electronic address: chingtat.lai@uwa.edu.au.
  • Gridneva Z; ABREAST Network, Perth, WA 6000, Australia; UWA Centre for Human Lactation Research and Translation, Crawley, WA 6009, Australia; School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia. Electronic address: zoya.gridneva@uwa.edu.au.
  • Leghi GE; School of Agriculture, Food and Wine, The University of Adelaide, Urrbrae, South Australia 5064, Australia. Electronic address: gabriela.leghivoyer@gmail.com.
  • Netting MJ; Women and Kids Theme, South Australian Health and Medical Research Institute (SAHMRI), North Terrace, South Australia 5000, Australia; Discipline of Paediatrics, The University of Adelaide, North Adelaide, South Australia 5006, Australia; Women's and Children's Hospital, North Adelaide, South Austra
  • Wlodek ME; School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, 3010, Australia. Electronic address: m.wlodek@unimelb.edu.au.
  • Muhlhausler BS; School of Agriculture, Food and Wine, The University of Adelaide, Urrbrae, South Australia 5064, Australia; CSIRO, Adelaide, South Australia 5000, Australia. Electronic address: bev.muhlhausler@csiro.au.
  • Zhou X; ABREAST Network, Perth, WA 6000, Australia; UWA Centre for Human Lactation Research and Translation, Crawley, WA 6009, Australia; School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia. Electronic address: xiaojie.zhou@uwa.edu.au.
  • Payne MS; Division of Obstetrics and Gynaecology, School of Medicine, The University of Western Australia, Subiaco, WA 6008, Australia. Electronic address: matthew.payne@uwa.edu.au.
  • Geddes DT; ABREAST Network, Perth, WA 6000, Australia; UWA Centre for Human Lactation Research and Translation, Crawley, WA 6009, Australia; School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia. Electronic address: donna.geddes@uwa.edu.au.
J Nutr Biochem ; : 109760, 2024 Sep 07.
Article en En | MEDLINE | ID: mdl-39251146
ABSTRACT
It is known that human milk (HM)1 antimicrobial protein composition varies during lactation. However, the impact of maternal diet on these antimicrobial proteins, particularly lactoferrin and lysozyme remains unknown. In addition, it is unclear whether daily, circadian, and between breast variations exist for lactoferrin and lysozyme concentrations. We investigated the impact of a low sugar, low fat, high fibre dietary intervention on HM lysozyme and lactoferrin concentrations. HM was sampled across a 3-week period; daily, at different times of day, and from both breasts to measure the level of intraindividual variation. The intervention significantly reduced maternal sugar, total fat, and saturated fat intake. HM lactoferrin concentration declined significantly over the course of the intervention however the effect size was relatively small. In addition, lactoferrin and lysozyme concentrations were variable over time, and differed significantly within and across the day but not between breasts.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Nutr Biochem Asunto de la revista: BIOQUIMICA / CIENCIAS DA NUTRICAO Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Nutr Biochem Asunto de la revista: BIOQUIMICA / CIENCIAS DA NUTRICAO Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos