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Research progress of traditional Chinese medicine in the treatment of ischemic stroke by regulating mitochondrial dysfunction.
Wang, Niuniu; Chen, Jun; Dang, Yanning; Zhao, Xinlin; Tibenda, Jonnea Japhet; Li, Nuan; Zhu, Yafei; Wang, Xiaobo; Zhao, Qipeng; Sun, Lei.
Afiliación
  • Wang N; School of Pharmacy, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China.
  • Chen J; Department of Critical Care Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
  • Dang Y; School of Pharmacy, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China.
  • Zhao X; School of Pharmacy, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China.
  • Tibenda JJ; School of Pharmacy, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China.
  • Li N; School of Pharmacy, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China.
  • Zhu Y; School of Nursing, Ningxia Medical University, Yinchuan, China.
  • Wang X; Innovative Institute of Chinese Medicine and Pharmacy/Academy for Interdiscipline, Chengdu University of Traditional Chinese Medicine, Chengdu, China. Electronic address: VitaDrwang@cdutcm.edu.cn.
  • Zhao Q; School of Pharmacy, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China. Electronic address: zhqp623@nxmu.edu.cn.
  • Sun L; School of Pharmacy, Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, China. Electronic address: Leisun-0@nxmu.edu.cn.
Life Sci ; 357: 123045, 2024 Sep 07.
Article en En | MEDLINE | ID: mdl-39251017
ABSTRACT
Ischemic stroke (IS) is a severe cerebrovascular disease with increasing incidence and mortality rates in recent years. The pathogenesis of IS is highly complex, with mitochondrial dysfunction playing a critical role in its onset and progression. Thus, preserving mitochondrial function is a pivotal aspect of treating ischemic brain injury. In response, there has been growing interest among scholars in the regulation of mitochondrial function through traditional Chinese medicine (TCM), including herb-derived compounds, individual herbs, and herbal prescriptions. This article reviews recent research on the mechanisms of mitochondrial dysfunction in IS and explores the potential of TCM in treating this condition by targeting mitochondrial dysfunction.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Life Sci Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Life Sci Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos