Your browser doesn't support javascript.
loading
Epidemiology, treatment outcome and resistance profile of pulmonary tuberculosis cases at the Niamey national anti-tuberculosis center in Niger: a retrospective study.
Djika, Mamane; Koudokpon, Charles Hornel; Dougnon, Victorien Tamègnon; Sanoussi, N'dira; Alphazazi, Soumana; Ballé, Boubacar; Daouda, Hassane; Assogba, Phénix; Bankole, Honoré; Agbangla, Clément.
Afiliación
  • Djika M; National Anti-Tuberculosis Center, National Tuberculosis Control Program, Niamey, Niger.
  • Koudokpon CH; Laboratory of Molecular Genetics and Genome analysis, Faculty of Science and Technology, University of Abomey-Calavi, UAC, Cotonou, Benin.
  • Dougnon VT; Research Unity of Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou, Benin.
  • Sanoussi N; Research Unity of Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou, Benin.
  • Alphazazi S; Laboratoire de Référence des Mycobactéries, Centre National Hospitalier Universitaire de Pneumo-Phtisiologie de Cotonou, National Tuberculosis Programme, Cotonou, Benin.
  • Ballé B; National Anti-Tuberculosis Center, National Tuberculosis Control Program, Niamey, Niger.
  • Daouda H; National Anti-Tuberculosis Center, National Tuberculosis Control Program, Niamey, Niger.
  • Assogba P; National Anti-Tuberculosis Center, National Tuberculosis Control Program, Niamey, Niger.
  • Bankole H; Research Unity of Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou, Benin.
  • Agbangla C; Research Unity of Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou, Benin.
Pan Afr Med J ; 47: 214, 2024.
Article en En | MEDLINE | ID: mdl-39247768
ABSTRACT

Introduction:

tuberculosis remains a major public health problem, with continuing high levels of prevalence, and mortality. In Niger, the incidence of tuberculosis remains high. This study aims to investigate the epidemiology of pulmonary tuberculosis at the National Anti-Tuberculosis Center of Niamey in Niger.

Methods:

this study used a quantitative approach with a retrospective and descriptive design. Data were obtained from positive pulmonary tuberculosis cases detected by microscopy on Ziehl-Neelsen stained sputum at the National Anti-Tuberculosis Center (NATC) in Niamey, Niger covered the period between June 2017 and January 2020. 955 pulmonary TB patients were recorded whose diagnosis was based either on clinical-radiological arguments (thus negative microscopy) or positive microscopy. This form was used to collect data recorded in the clinical case registers, registers, and Excel files of the GeneXpert platform of the NATC laboratory.

Results:

eighty-nine-point eleven percent (89.11%) of the patients were microscopy-positive. Among the study population, men were the most affected by tuberculosis with 80.03%. The 25-34 age group, representing 23.77%, was the most affected. 6.93% of patients were co-infected with tuberculosis and HIV. All patients were put on treatment, with a therapeutic success rate of 72.38% and a therapeutic failure rate of 10.95%. Among the cases of therapeutic failure, 80.90% had Mycobacterium tuberculosis complex detected and 27.14% were resistant to Rifampicin.

Conclusion:

Niger continues to have a tuberculosis epidemic which requires monitoring. Improving the diagnostic system for more effective management of the disease is important for appropriate diagnosis and treatment.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Mycobacterium tuberculosis / Antituberculosos País/Región como asunto: Africa Idioma: En Revista: Pan Afr Med J Año: 2024 Tipo del documento: Article País de afiliación: Níger Pais de publicación: Uganda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Mycobacterium tuberculosis / Antituberculosos País/Región como asunto: Africa Idioma: En Revista: Pan Afr Med J Año: 2024 Tipo del documento: Article País de afiliación: Níger Pais de publicación: Uganda