Your browser doesn't support javascript.
loading
Sarcopenic obesity is associated with cardiometabolic multimorbidity in Chinese middle-aged and older adults: a cross-sectional and longitudinal study.
Yu, Bingyan; Jia, Shize; Sun, Tiantian; Liu, Jieliang; Jin, Junguo; Zhang, Shanghong; Xiao, Qiyao; Dong, Haojian; Ou, Yanqiu.
Afiliación
  • Yu B; Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China.
  • Jia S; School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
  • Sun T; Department of Hematology, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518107, China.
  • Liu J; Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China.
  • Jin J; Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China.
  • Zhang S; Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China.
  • Xiao Q; School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
  • Dong H; Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China; Nyingchi People's Hospital, Nyingchi 860000, Tibet, China. Electronic address: donghaojian@gdph.org.cn.
  • Ou Y; Department of Cardiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China. Electronic address: ouyanqiu@gdph.org.cn.
J Nutr Health Aging ; 28(10): 100353, 2024 Sep 07.
Article en En | MEDLINE | ID: mdl-39244787
ABSTRACT

OBJECTIVES:

Sarcopenic obesity (SO) has been found to increase the risk of metabolic disorders, however, its relationship with cardiometabolic multimorbidity (CMM) remains unexplored. This study aims to investigate the potential association between SO and CMM in the middle-aged and older population.

METHODS:

Our study subjects were from CHARLS. SO was defined as the combination of impaired grip strength (grip strength <28 kg for men and <18 kg for women) and increased body mass index (BMI ≥25 kg/m2). CMM was defined as having two or more cardiometabolic diseases, including diabetes mellitus, stroke, and heart disease. The participants were divided into four groups according to their sarcopenia and obesity status, and logistic regression analysis was used to examine the association between SO and CMM.

RESULTS:

A total of 15,252 study subjects were included in the cross-sectional study, with an average age of 60.6 years and a male proportion of 47.4%. In the cross-sectional analysis conducted in 2015, the prevalence of CMM was highest in the SO group (9.1%), followed by the obesity (3.7%) and sarcopenia (3.5%) group. After adjustment for confounding factors, SO [OR (95%CI) 2.453 (1.742-3.455)], sarcopenia [OR (95% CI) 1.601 (1.157-2.217)], obesity [OR (95% CI) 1.446 (1.107-1.888)] were all observed to be associated with CMM, with the strongest association in the SO group. Furthermore, in the longitudinal analysis, only the SO group demonstrated a significant risk for developing CMM [OR (95% CI) 2.302 (1.239-4.228)].

CONCLUSIONS:

SO was independently and positively associated with CMM in middle-aged and older population.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Nutr Health Aging Asunto de la revista: CIENCIAS DA NUTRICAO / GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Nutr Health Aging Asunto de la revista: CIENCIAS DA NUTRICAO / GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia