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Clinical maternal risk parameters for the occurrence of maternal and fetal complications during preeclampsia in Congolese women.
Tshibuela Beya, Dophie; Kimena Nyota, Passy; Muwonga Masidi, Jérémie; Lumbala Kilembo, Elisabeth; Nkodila Natuhoyila, Aliocha; Verdonck, Fons; Spitz, Bernard; Pierre Elongi Moyene, Jean.
Afiliación
  • Tshibuela Beya D; Department of Medical Biology, Clinical Biology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Congo.
  • Kimena Nyota P; Department of Medical Biology, Clinical Biology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Congo.
  • Muwonga Masidi J; Department of Medical Biology, Clinical Biology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Congo.
  • Lumbala Kilembo E; Department of Gynaecology-Obstétrics, Cliniques Universitaires de Kinshasa, Kinshasa, Congo.
  • Nkodila Natuhoyila A; Department of Internal Medicine, Cliniques Universitaires de Kinshasa, Kinshasa, Congo.
  • Verdonck F; Department of Physiology, KU, Leuven, Belgium.
  • Spitz B; Department of Gynaecology-Obstetrics, KU, Leuven, Belgium.
  • Pierre Elongi Moyene J; Department of Gynaecology-Obstetrics, Hôpital Général de Référence de Kinshasa, Kinshasa, Congo. Electronic address: elongi2002@yahoo.fr.
Pregnancy Hypertens ; 38: 101156, 2024 Sep 06.
Article en En | MEDLINE | ID: mdl-39243693
ABSTRACT
Several studies have demonstrated that predicting complications of preeclampsia up to 48 h before their occurrence enhances clinical management. This predictive ability allows for rational approaches in dealing with groups at high risk of maternal-fetal complications.

OBJECTIVE:

This study aims to identify the clinical parameters strongly associated with maternal-fetal complications during preeclampsia in Congolese pregnant women.

METHOD:

A descriptive and analytical study was conducted in the provincial city of Kinshasa from July 2018 to December 2021. The study population consisted of pregnant women with preeclampsia in three maternity units in Kinshasa. Determinants of complications were assessed using univariate and multivariate logistic regression.

RESULTS:

In univariate logistic regression models, obesity, a history of hypertension, severe hypertension, and SpO2 < 90 % were identified as determinants of maternal-fetal complications. Conversely, a history of preeclampsia, treatment with MgSO4, or a combination of AntiHTA and MgSO4 reduced the risk of complications. In the multivariate model, after adjusting for all significant variables in the univariate model, severe hypertension, obesity, and SpO2 < 90 % were identified as independent determinants of maternal-fetal complications. The risk of complication was multiplied by 5 for severe hypertension, by 4 for obesity, and by 2 for SpO2 < 90 %. However, treating women with MgSO4 or a combination of AntiHTA and MgSO4 reduced the risk of complications by a factor of 4 and 6, respectively.

CONCLUSION:

The presence of symptoms is more useful in predicting complications of preeclampsia than their absence in ruling out adverse events.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pregnancy Hypertens Año: 2024 Tipo del documento: Article País de afiliación: Congo Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pregnancy Hypertens Año: 2024 Tipo del documento: Article País de afiliación: Congo Pais de publicación: Países Bajos