A one-way street recognition approach to mediate allogeneic immune cell therapies.
Cell Stem Cell
; 31(9): 1239-1240, 2024 Sep 05.
Article
en En
| MEDLINE
| ID: mdl-39241752
ABSTRACT
CD54 and CD58 are adhesion proteins that mediate efficient immune synapse formation. Hammer et al. now show that the abrogation of these molecules in T and NK cells prevents their immune rejection while maintaining their effector function. These findings should significantly help advance our efforts to generate "off-the-shelf" allogeneic products.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Células Asesinas Naturales
Límite:
Humans
Idioma:
En
Revista:
Cell Stem Cell
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos