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The state of systemic immunity in congenital cleft lip and palate patients with diseases of oral cavity tissues.
Timokhina, Tetiana O; Holubchenko, Oleh I; Cherkasova, Olena V; Melnyk, Bohdan M.
Afiliación
  • Timokhina TO; BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE, NATIONAL SPECIALIZED CHILDREN'S HOSPITAL "OKHMATDYT", KYIV, UKRAINE.
  • Holubchenko OI; NATIONAL SPECIALIZED CHILDREN'S HOSPITAL "OKHMATDYT", KYIV, UKRAINE.
  • Cherkasova OV; BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
  • Melnyk BM; BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Wiad Lek ; 77(7): 1364-1371, 2024.
Article en En | MEDLINE | ID: mdl-39241134
ABSTRACT

OBJECTIVE:

Aim:

To determine the state of dental health and the state of systemic immunity in patients in congenital cleft lip and palate patients. PATIENTS AND

METHODS:

Materials and

Methods:

The dental status and immunologic tests of 74 patients age 8-18 years old with congenital cleft lip and palate was analyzed 43 children with unilateral and 31 children with bilateral complete combined cleft lip, alveolar process, hard and soft palate.

RESULTS:

Results:

Indicators of the prevalence and intensity of the caries process in patients with congenital congenital complete cleft lip, alveolar process, hard and soft palate were high, especially in children with bilateral cleft lip and palate - the decompensated course of caries was determined in 41.93% patients, with unilateral - 23.25%. Сhronic catarrhal gingivitis was the most common in both groups of patients - the average severity of gingivitis prevailed - 51.16% with congenital unilateral cleft lip and palate and 51.61% - with bilateral. Atopic cheilitis, glossitis and chronic recurrent aphthous stomatitis were common. This patients have significant changes in the cellular chain of the immune system with a deficiency of the main phenotypes of lymphocytes - CD4+ CD8+ and inflammatory bacterial changes in blood serum.

CONCLUSION:

Conclusions:

Patients of unilateral and bilateral complete combined cleft lip, alveolar process, hard and soft palate have significant changes in the dental status and in the cellular chain of the immune system. The level of manifestation of these changes is directly proportional to the extent of localization of the pathology - unilateral or bilateral.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Labio Leporino / Fisura del Paladar Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Wiad Lek Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: Ucrania Pais de publicación: Polonia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Labio Leporino / Fisura del Paladar Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Wiad Lek Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: Ucrania Pais de publicación: Polonia