A potential biomarker for age-related macular degeneration disease: iris freckles.
Int J Retina Vitreous
; 10(1): 62, 2024 Sep 05.
Article
en En
| MEDLINE
| ID: mdl-39238056
ABSTRACT
BACKGRAUND To determine the potential relationship between age-related macular degeneration and iris freckles. METHOD:
In this case-control study, iris photographs of 300 eyes of 300 patients diagnosed with age-related macular degeneration and 300 eyes of 300 healthy volunteers were obtained with the help of a high-resolution mobile phone camera. The evaluated iris photographs were classified according to the Descriptive Iris Color Classification Scale.RESULTS:
The average age of the AMD group is 73.05 ± 6.93, and the average age of the control group is 73.43 ± 5.72. (p = 0.124) While freckles were present in 200 (66.7%) of the patients in the AMD group, freckles were not observed in 100 patients (33.3%) of AMD group. While freckles were present in 142 (47.3%) of the patients in the control group, freckles were not observed in 158 of control group(52.7%). There was a significant difference in the presence of freckles between the two groups. (p < 0.001) The average number of freckles in the AMD group was 3.97 ± 3.07, and the number of freckles in the control group was 3.06 ± 2.55. (p = 0.001)CONCLUSION:
We think that evaluation of iris details, especially the presence of iris freckles, should be used routinely in age-related macular degeneration screening. The risk of age-related macular degeneration can be predicted by evaluating iris details, which is an easy and inexpensive method.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Int J Retina Vitreous
Año:
2024
Tipo del documento:
Article
País de afiliación:
Turquía
Pais de publicación:
Reino Unido