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Determinants of In-hospital Death in Non-ST-segment Elevation Myocardial Infarction with Triple-vessel Disease.
Tokunaga, Yuki; Sakakura, Kenichi; Jinnouchi, Hiroyuki; Taniguchi, Yousuke; Yamamoto, Kei; Tsukui, Takunori; Hatori, Masashi; Kasahara, Taku; Ishibashi, Shun; Watanabe, Yusuke; Seguchi, Masaru; Fujita, Hideo.
Afiliación
  • Tokunaga Y; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Sakakura K; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Jinnouchi H; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Taniguchi Y; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Yamamoto K; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Tsukui T; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Hatori M; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Kasahara T; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Ishibashi S; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Watanabe Y; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Seguchi M; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
  • Fujita H; Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Japan.
Intern Med ; 2024 Sep 04.
Article en En | MEDLINE | ID: mdl-39231675
ABSTRACT
Objective Triple-vessel disease (TVD) is a well-established prognostic factor for patients with acute myocardial infarction (AMI). However, there is a paucity of literature regarding the risk factors for in-hospital death in patients with non-ST-segment elevation myocardial infarction (NSTEMI) and TVD. In this retrospective study, we examined the determinants of in-hospital death in patients with NSTEMI and TVD who underwent percutaneous coronary intervention (PCI) for culprit lesions. Methods The primary objective of this study was to identify the factors associated with in-hospital death using a multivariate analysis. We included 253 patients with NSTEMI and TVD and divided them into a survivor group (n=239) and an in-hospital death group (n=14). Results Systolic blood pressure (SBP) at admission was significantly higher in the survivor group than in the in-hospital death group. The estimated glomerular filtration rate (eGFR) was also higher in the survivor group than in the in-hospital death group. In the multivariate logistic regression analysis, in-hospital death was inversely associated with the SBP at admission (odds ratio [OR] 0.984, 95% confidence interval [CI] 0.970-0.999, p<0.035) and eGFR (OR 0.966, 95% CI 0.939-0.994, p=0.019) and was associated with cardiopulmonary arrest (CPA) before PCI (OR 8.448, 95%CI 1.863-38.309, p=0.006). Conclusion In-hospital death was associated with CPA before PCI and inversely associated with the SBP at admission and eGFR in patients with NSTEMI and TVD who underwent PCI for the culprit lesion. It may be important to recognize these high-risk features in order to improve the clinical outcomes of patients with NSTEMI and TVD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón