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Advances in Technology for Melanoma Diagnosis and Prognosis: An Expert Consensus Panel.
J Drugs Dermatol ; 23(9): 774-781, 2024 09 01.
Article en En | MEDLINE | ID: mdl-39231082
ABSTRACT

BACKGROUND:

Cutaneous melanoma (CM) is associated with a higher mortality rate than most other skin cancers. The purpose of this expert consensus panel was to review the published literature on new technological advancements for the diagnosis and prognosis for CM and provide updated guidance on their usage.

METHODS:

A comprehensive literature search of PubMed, Scopus, and Google Scholar was completed for English-language original research articles on the topics of non-invasive diagnostic and prognostic testing for CM, including gene expression profiling (GEP) and electrical impedance spectroscopy (EIS). A panel of 10 dermatologists with significant expertise in the treatment of CM gathered to review the articles and create consensus statements. A modified Delphi process was used to approve each statement and a strength of recommendation was assigned using widely recognized Strength of Recommendation Taxonomy criteria.

RESULTS:

The literature search produced 200 articles that met the criteria. A screening of the studies resulted in 19 articles. These were distributed to all panelists for review prior to a roundtable discussion. The panel unanimously voted to adopt 7 consensus statements and recommendations, 5 of which were given a strength of "A", 1 of which was given a strength of "B," and 1 of which was given a strength of "C".

CONCLUSION:

The 2-GEP test and EIS can aid in the precise diagnosis of clinically indeterminate lesions and the 23-GEP test can be used when histopathology is equivocal. The 31-GEP test can enhance prognostic assessment beyond AJCC8 staging and improve clinical decision-making. J Drugs Dermatol. 2024;23(9)774-781. doi10.36849/JDD.8365R1.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Consenso / Espectroscopía Dieléctrica / Melanoma Límite: Humans Idioma: En Revista: J Drugs Dermatol Asunto de la revista: DERMATOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Consenso / Espectroscopía Dieléctrica / Melanoma Límite: Humans Idioma: En Revista: J Drugs Dermatol Asunto de la revista: DERMATOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos