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IL-6 and stroke recurrence in ischemic stroke.
Jiang, Yuanfeng; Fan, Tao.
Afiliación
  • Jiang Y; Spine Center, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
  • Fan T; Spine Center, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Biomark Med ; 18(17-18): 739-747, 2024.
Article en En | MEDLINE | ID: mdl-39230474
ABSTRACT

Objective:

This study aimed to evaluate the predictive value of IL-6 for stroke recurrence in acute ischemic stroke.

Methods:

Patients who were admitted within 48 h of onset were included. At 3-month, stroke recurrence was assessed. IL-6 levels were measured in serum samples taken upon admission.

Results:

Out of the 305 patients, 47 (15.4%) experienced a stroke recurrence. The risk of stroke recurrence increased by 8% (OR 1.08; 95% CI 1.04-1.11; p < 0.001) for every 1 pg/ml increase in IL-6 serum level, both in unadjusted and adjusted analyses (6%; OR 1.06; 95% CI 1.02-1.10; p = 0.001).

Conclusion:

The study supports the usefulness of IL-6 as a predictive biomarker for stroke recurrence after acute ischemic stroke.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recurrencia / Biomarcadores / Interleucina-6 / Accidente Cerebrovascular Isquémico Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Biomark Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recurrencia / Biomarcadores / Interleucina-6 / Accidente Cerebrovascular Isquémico Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Biomark Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido