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Exosomes That Have Different Cellular Origins Followed by the Impact They Have on Prostate Tumor Development in the Tumor Microenvironment.
Huang, Cong; Zhang, Jialong; Wang, Hongzhi; Liang, Chaozhao.
Afiliación
  • Huang C; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, China.
  • Zhang J; Institute of Urology, Anhui Medical University, Hefei, China.
  • Wang H; Key Laboratory of Genitourinary Diseases Anhui Province, Anhui Medical University, Hefei, China.
  • Liang C; Department of Urology, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, China.
Cancer Rep (Hoboken) ; 7(9): e70001, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39229670
ABSTRACT

BACKGROUND:

Prostate cancer (PCa) is the most common urinary tumor with the highest incidence rate and the second among the leading causes of death worldwide for adult males. In the worldwide cancer incidence rate, PCa is on the increase. The cancerous cells in the prostate and cells in the microenvironment surrounding the tumor communicate through signal transduction, which is crucial for the development and spread of PCa. RECENT

FINDINGS:

Exosomes are nanoscale vesicles released into body fluids by various cells that can aid intercellular communication by releasing nucleic acids and proteins. Exosomes published by different types of cells in the tumor microenvironment can have varying impacts on the proliferation and growth of tumor cells via various signaling pathways, modes of action, and secreted cytokines.

CONCLUSION:

The main purpose of this review is to describe the effects of different cell-derived exosomes in the tumor microenvironment of PCa on the progression of tumor cells, as well as to summarize and discuss the prospects for the application of exosomes in the treatment and diagnosis of PCa.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Exosomas / Microambiente Tumoral Límite: Animals / Humans / Male Idioma: En Revista: Cancer Rep (Hoboken) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Exosomas / Microambiente Tumoral Límite: Animals / Humans / Male Idioma: En Revista: Cancer Rep (Hoboken) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos