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Peripheral artery disease risk factors: A focus on lipoprotein(a).
Dalla Vestra, Michele; Grolla, Elisabetta; Autiero, Giuliana; Presotto, Fabio.
Afiliación
  • Dalla Vestra M; Department of Internal Medicine, Ospedale dell'Angelo, 30174 Mestre-Venezia, Italy. Electronic address: micheledallavestra@gmail.com.
  • Grolla E; Department of Cardiology, Ospedale dell'Angelo, 30174 Mestre-Venezia, Italy.
  • Autiero G; Department of Internal Medicine, Ospedale dell'Angelo, 30174 Mestre-Venezia, Italy.
  • Presotto F; Department of Internal Medicine, Ospedale dell'Angelo, 30174 Mestre-Venezia, Italy.
Arch Cardiovasc Dis ; 117(10): 584-589, 2024 Oct.
Article en En | MEDLINE | ID: mdl-39227282
ABSTRACT
There is a well-established and strong link between high lipoprotein(a) concentration and coronary heart disease, but the evidence regarding peripheral artery disease and carotid atherosclerosis is not as conclusive. This review aims to summarize the relationships between lipoprotein(a), peripheral artery disease and carotid atherosclerosis, in order to try to understand the weight of lipoprotein(a) in determining the development, progression and any complications of atherosclerotic plaque at the carotid and peripheral artery level. There is currently no effective therapy to reduce lipoprotein(a) concentration, but understanding its significance as a vascular risk factor is the starting point to then explore (when effective therapies become available) if there is the possibility, even in patients with peripheral artery disease and carotid atherosclerosis, to achieve better control of the residual vascular risk that is ultimately induced by lipoprotein(a).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedades de las Arterias Carótidas / Lipoproteína(a) / Enfermedad Arterial Periférica Límite: Humans Idioma: En Revista: Arch Cardiovasc Dis Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedades de las Arterias Carótidas / Lipoproteína(a) / Enfermedad Arterial Periférica Límite: Humans Idioma: En Revista: Arch Cardiovasc Dis Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos