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The third symposium on treatment-induced neuroendocrine prostate cancer: insights and future directions.
Wang, Yuzhuo; Scurll, Joshua; Rascón, Itzel Astiazarán; Cui, Cassandra; Ni, Yuchao; Shi, Ace Mingchen; Gangadharannambiar, Priyadarsini; Wang, Yu; Akamatsu, Shusuke; Beltran, Himisha; Cox, Michael; Crea, Francesco; Daugaard, Mads; Dong, Xuesen; Haffner, Michael; He, Hansen; Jachetti, Elena; Kyprianou, Natasha; Li, Benyi; Ong, Christopher E; Rickman, David S; Sen, Triparna; Zhu, Helen He; Zoubeidi, Amina; Gleave, Martin E.
Afiliación
  • Wang Y; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Scurll J; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
  • Rascón IA; BC Cancer Research Institute, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.
  • Cui C; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Ni Y; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
  • Shi AM; BC Cancer Research Institute, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.
  • Gangadharannambiar P; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Wang Y; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
  • Akamatsu S; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Beltran H; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
  • Cox M; BC Cancer Research Institute, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.
  • Crea F; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Daugaard M; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
  • Dong X; BC Cancer Research Institute, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.
  • Haffner M; Open University, School of Life Health & Chemical Sciences, Milton Keynes, MK7 6AA, UK.
  • He H; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Jachetti E; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
  • Kyprianou N; BC Cancer Research Institute, BC Cancer, Vancouver, BC, V5Z 1L3, Canada.
  • Li B; Department of Urology, Nagoya University Graduate School of Medicine, Aichi, 466-8550, Japan.
  • Ong CE; Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Rickman DS; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Sen T; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
  • Zhu HH; Open University, School of Life Health & Chemical Sciences, Milton Keynes, MK7 6AA, UK.
  • Zoubeidi A; Vancouver Prostate Centre, Vancouver, BC, V6H 3Z6, Canada.
  • Gleave ME; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, V5Z 1M9, Canada.
Epigenomics ; 16(17): 1129-1132, 2024.
Article en En | MEDLINE | ID: mdl-39225130
ABSTRACT
Neuroendocrine prostate cancer (NEPC) is a rare and aggressive subtype of prostate cancer (PCa), emerging from advanced treatments and characterized by loss of androgen receptor (AR) signaling and neuroendocrine features, leading to rapid progression and treatment resistance. The third symposium on treatment-induced NEPC, held from 21 to 23 June 2024, at Harrison Hot Springs Resort, BC, Canada, united leading global researchers and clinicians. Sponsored by the Vancouver Prostate Centre (VPC), Canadian Institute of Health Research, Prostate Cancer Foundation Canada and Pharma Planter Inc, the event focused on the latest NEPC research and innovative treatment strategies. Co-chaired by Drs. Yuzhuo Wang and Martin Gleave, the symposium featured sessions on NEPC's historical context, molecular pathways, epigenetic regulation and the role of the tumor microenvironment and metabolism in its progression. Keynotes from experts like Dr. Himisha Beltran and Dr. Martin Gleave highlighted the complexity of NEPC. The Emerging Talent session showcased new research, pointing to the future of NEPC treatment. The symposium concluded with a consensus on the need for early detection, targeted therapies and personalized medicine to effectively combat NEPC, emphasizing the importance of global collaboration in advancing NEPC understanding and treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata Límite: Humans / Male Idioma: En Revista: Epigenomics Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata Límite: Humans / Male Idioma: En Revista: Epigenomics Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido