Your browser doesn't support javascript.
loading
Integrating frontiers: a holistic, quantum and evolutionary approach to conquering cancer through systems biology and multidisciplinary synergy.
Casotti, Matheus Correia; Meira, Débora Dummer; Zetum, Aléxia Stefani Siqueira; Campanharo, Camilly Victória; da Silva, Danielle Ribeiro Campos; Giacinti, Giulia Maria; da Silva, Iris Moreira; Moura, João Augusto Diniz; Barbosa, Karen Ruth Michio; Altoé, Lorena Souza Castro; Mauricio, Lorena Souza Rittberg; Góes, Luíza Santa Brígida de Barros; Alves, Lyvia Neves Rebello; Linhares, Sarah Sophia Guedes; Ventorim, Vinícius do Prado; Guaitolini, Yasmin Moreto; Dos Santos, Eldamária de Vargas Wolfgramm; Errera, Flavia Imbroisi Valle; Groisman, Sonia; de Carvalho, Elizeu Fagundes; de Paula, Flavia; de Sousa, Marcelo Victor Pires; Fechine, Pierre Basílio Almeida; Louro, Iuri Drumond.
Afiliación
  • Casotti MC; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Meira DD; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Zetum ASS; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Campanharo CV; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • da Silva DRC; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Giacinti GM; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • da Silva IM; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Moura JAD; Laboratório de Oncologia Clínica e Experimental, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Barbosa KRM; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Altoé LSC; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Mauricio LSR; Laboratório de Oncologia Clínica e Experimental, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Góes LSBB; Grupo de Bioanalítica, Microfabricação e Separações (BioMicS), Universidade de São Paulo (USP), São Carlos, SP, Brazil.
  • Alves LNR; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Linhares SSG; Laboratório de Estudos Neuroquímicos, Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil.
  • Ventorim VDP; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Guaitolini YM; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Dos Santos EVW; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Errera FIV; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • Groisman S; Instituto de Biologia Roberto Alcântara Gomes (IBRAG), Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil.
  • de Carvalho EF; Instituto de Biologia Roberto Alcântara Gomes (IBRAG), Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil.
  • de Paula F; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
  • de Sousa MVP; Bright Photomedicine, Tergos Pesquisa E Ensino S.A., São Paulo, SP, Brazil.
  • Fechine PBA; Group of Chemistry of Advanced Materials (GQMat), Department of Analytical Chemistry and Physical-Chemistry, Federal University of Ceará (UFC), Fortaleza, CE, Brazil.
  • Louro ID; Núcleo de Genética Humana e Molecular, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil.
Front Oncol ; 14: 1419599, 2024.
Article en En | MEDLINE | ID: mdl-39224803
ABSTRACT
Cancer therapy is facing increasingly significant challenges, marked by a wide range of techniques and research efforts centered around somatic mutations, precision oncology, and the vast amount of big data. Despite this abundance of information, the quest to cure cancer often seems more elusive, with the "war on cancer" yet to deliver a definitive victory. A particularly pressing issue is the development of tumor treatment resistance, highlighting the urgent need for innovative approaches. Evolutionary, Quantum Biology and System Biology offer a promising framework for advancing experimental cancer research. By integrating theoretical studies, translational methods, and flexible multidisciplinary clinical research, there's potential to enhance current treatment strategies and improve outcomes for cancer patients. Establishing stronger links between evolutionary, quantum, entropy and chaos principles and oncology could lead to more effective treatments that leverage an understanding of the tumor's evolutionary dynamics, paving the way for novel methods to control and mitigate cancer. Achieving these objectives necessitates a commitment to multidisciplinary and interprofessional collaboration at the heart of both research and clinical endeavors in oncology. This entails dismantling silos between disciplines, encouraging open communication and data sharing, and integrating diverse viewpoints and expertise from the outset of research projects. Being receptive to new scientific discoveries and responsive to how patients react to treatments is also crucial. Such strategies are key to keeping the field of oncology at the forefront of effective cancer management, ensuring patients receive the most personalized and effective care. Ultimately, this approach aims to push the boundaries of cancer understanding, treating it as a manageable chronic condition, aiming to extend life expectancy and enhance patient quality of life.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza