Structure and function of bacterial transcription regulators of the SorC family.
Transcription
; : 1-22, 2024 Sep 03.
Article
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| MEDLINE
| ID: mdl-39223991
ABSTRACT
The SorC family is a large group of bacterial transcription regulators involved in controlling carbohydrate catabolism and quorum sensing. SorC proteins consist of a conserved C-terminal effector-binding domain and an N-terminal DNA-binding domain, whose type divides the family into two subfamilies SorC/DeoR and SorC/CggR. Proteins of the SorC/CggR subfamily are known to regulate the key node of glycolysis-triose phosphate interconversion. On the other hand, SorC/DeoR proteins are involved in a variety of peripheral carbohydrate catabolic pathways and quorum sensing functions, including virulence. Despite the abundance and importance of this family, SorC proteins seem to be on the periphery of scientific interest, which might be caused by the fragmentary information about its representatives. This review aims to compile the existing knowledge and provide material to inspire future questions about the SorC protein family.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Transcription
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos