Delivery Hospitalization Cardiac and Respiratory Complications during SARS-CoV-2 Delta Variant Dominance.
Am J Perinatol
; 2024 Sep 02.
Article
en En
| MEDLINE
| ID: mdl-39222923
ABSTRACT
In 2021, the SARS-CoV-2 Delta variant rapidly proliferated and became dominant. Some but not all research evidence supports that Delta was associated with increased maternal risk. The purpose of this study was to determine whether Delta was associated with risk for cardiac and respiratory complications in a national sample. Of an estimated 3,495,188 delivery hospitalizations in 2021, 1.8% of pre-Delta deliveries (n=29,580) (January-June) and 2.1% of Delta-period deliveries (n=37,545) (July-December) had a COVID-19 diagnosis. The Delta period was associated with increased adjusted odds of respiratory complications (aOR 1.54, 95% CI 1.41, 1.69) and cardiac SMM (aOR 1.54, 95% CI 1.40, 1.69). Among deliveries with a COVID diagnosis, the Delta period was associated with higher incidence of respiratory complications (8.4% versus 3.7%) and cardiac SMM (8.4% versus 3.5%) (p<0.01 for both). These findings corroborate prior clinical studies suggesting that the Delta strain was associated with an increased maternal population-level clinical burden.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Am J Perinatol
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos