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The association between visceral adipose accumulation and hyperuricemia risk among Chinese elder individuals: A nationwide prospective cohort study.
Han, Yutong; Li, Jiang; Bai, Wendi.
Afiliación
  • Han Y; Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
  • Li J; Guangzhou Nansha district Center for Disease Control and Prevention, Nansha District, Guangzhou 511455, China.
  • Bai W; Guangzhou Nansha district Center for Disease Control and Prevention, Nansha District, Guangzhou 511455, China.
Prev Med Rep ; 45: 102843, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39220610
ABSTRACT

Background:

Lipid accumulation product (LAP), visceral adiposity index (VAI) and Chinese visceral adiposity index (CVAI) are proposed indices of visceral adipose accumulation. This study aimed to explore their relationship and temporal changes with hyperuricemia (HUA) development in a Chinese population.

Methods:

A total of 4268 participants aged ≥45 years from the baseline survey of the China Health and Retirement Longitudinal Study were followed up for 4 years (from 2011 to 2015). The relationships among VAI, LAP, CVAI and HUA were analyzed using logistic regression. The predictive abilities of the VAI, LAP and CVAI for HUA were compared using receiver operating characteristic curves. Nonlinear relationships between the indices and HUA were analyzed using restricted cubic spline regression.

Results:

During the four-year follow-up, 415 (9.72 %) patients experienced incident HUA . Elevated baseline VAI (odds ratio (OR) 1.19 (95 % confidence interval (95 %CI 1.10, 1.29)), LAP (OR 1.21 (95 % CI 1.09, 1.34)) and CVAI (OR 1.19 (95 % CI 1.02, 1.40)) were significantly correlated with increased HUA risk (all P < 0.05). Compared to individuals with consistently low VAI,CVAIor LAP levels, those with elevated or consistently high levels of these indicators are more likely to have HUA. The area under curve (AUC) was slightly greater and more significant for the CVAI (AUC=0.641) than for the VAI (AUC=0.604) and LAP (AUC=0.628) (P < 0.05).

Conclusion:

VAI, LAP and CVAI can predict HUA, with CVAI more efficient than VAI and LAP. Early management can lessen the burden of HUA in Chinese people aged 45 years or older with elevated CVAI levels.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Prev Med Rep Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Prev Med Rep Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos