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High-quality FLORET UTE imaging for clinical translation.
Willmering, Matthew M; Krishnamoorthy, Guruprasad; Robison, Ryan K; Rosenberg, Jens T; Woods, Jason C; Pipe, James G.
Afiliación
  • Willmering MM; Center for Pulmonary Imaging Research, Division of Pulmonary Medicine, Cincinnati Children's Hospital, Cincinnati, Ohio, USA.
  • Krishnamoorthy G; Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA.
  • Robison RK; Philips Healthcare, Rochester, Minnesota, USA.
  • Rosenberg JT; Department of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
  • Woods JC; Philips Healthcare, Nashville, Tennessee, USA.
  • Pipe JG; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Magn Reson Med ; 2024 Sep 01.
Article en En | MEDLINE | ID: mdl-39219306
ABSTRACT

PURPOSE:

To develop a robust 3D ultrashort-TE (UTE) protocol that can reproducibly provide high-quality images, assessed by the ability to yield clinically diagnostic images, and is suitable for clinical translation. THEORY AND

METHODS:

Building on previous work, a UTE sampled with Fermat looped orthogonally encoded trajectories (FLORET) was chosen as a starting point due to its shorter, clinically reasonable scan times. Modifications to previous FLORET implementations included gradient waveform frequency limitations, a new trajectory ordering scheme, a balanced SSFP implementation, fast gradient spoiling, and full inline reconstruction. FLORET images were collected in phantoms and humans on multiple scanners and sites to demonstrate these improvements.

RESULTS:

The updates to FLORET provided high-quality images in phantom, musculoskeletal, and pulmonary applications. The gradient waveform modifications and new trajectory ordering scheme significantly reduced visible artifacts. Fast spoiling reduced acquisition time by 20%-28%. Across the various scanners and sites, the inline image quality was consistent and of diagnostic quality. Total image acquisition plus reconstruction time was less than 4 min for musculoskeletal and pulmonary applications with reconstructions taking less than 1 min.

CONCLUSION:

Recently developed improvements for the FLORET sequence have enabled robust, high-quality UTE acquisitions with short acquisition and reconstruction times. This enables clinical UTE imaging as demonstrated by the implementation of the sequence and acquisition on five MRI scanners, at three different sites, without the need for any additional system characterization or measurements.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Magn Reson Med Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Magn Reson Med Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos