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Alternansucrase as a key enabling tool of biotransformation from molecular features to applications: A review.
Chen, Gang; Khan, Imran Mahmood; Zhang, Tao; Campanella, Osvaldo H; Miao, Ming.
Afiliación
  • Chen G; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; College of Food and Health, Zhejiang Agriculture and Forest University, Hangzhou 311300, China.
  • Khan IM; Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute, University of Nottingham Ningbo China, Ningbo 315100, China.
  • Zhang T; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
  • Campanella OH; Department of Food Science and Technology, Ohio State University, Columbus, OH, USA.
  • Miao M; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China. Electronic address: miaoming@jiangnan.edu.cn.
Int J Biol Macromol ; 279(Pt 1): 135096, 2024 Aug 28.
Article en En | MEDLINE | ID: mdl-39214198
ABSTRACT
Alternansucrase (ASR), classified in GH70, produces unique α-glucans with alternating α-1,3 and α-1,6 glycosidic linkages in the backbone chain from renewable sucrose which is easily obtained from nature with low cost. ASR has synthesized many products with valuable functionalities that hold enormous commercial interest and promising applications. The influence of biocatalysis and fermentation parameters on the yields, and properties of products are critical for the propositions made to promote the enzyme application. Investigations on ASR have been compiled in the review to provide information on the enzyme, products and parameters. This review summarizes studies on the characteristics, conversion mechanism, products, and beneficial applications of ASR and exhibits structure-based technologies to improve enzyme activity, specificity, and thermostability for industrial applications. Finally, prospects for further development are also proposed for various ASR applications in food and other fields.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Biol Macromol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Biol Macromol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos