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Glioblastoma multiforme in a patient with neurofibromatosis type 1: a case report and review of literature.
Ayasa, Laith A; Rahhal, Sara; Najjar, Alaa Khaled; Suboh, Bashar N; Aliwaiai, Mohammed; Daqour, Ahmad M; Bakri, Izzeddin.
Afiliación
  • Ayasa LA; Al Quds University Faculty of Medicine, Mount of Olives St. 26, Sheikh Jarrah, P.O. Box 22246, Jerusalem 91513, Palestine.
  • Rahhal S; School of Medicine, The University of Jordan, Amman, Queen Rania St. Jubeiha, P.O. Box 11942, Amman, Jordan.
  • Najjar AK; Department of Neurosurgery, Al-Makassed Islamic Charitable Hospital, Jerusalem 97103, Palestine.
  • Suboh BN; Department of Neurosurgery, Al-Makassed Islamic Charitable Hospital, Jerusalem 97103, Palestine.
  • Aliwaiai M; Department of Neurosurgery, Al-Makassed Islamic Charitable Hospital, Jerusalem 97103, Palestine.
  • Daqour AM; Department of Neurosurgery, Al-Makassed Islamic Charitable Hospital, Jerusalem 97103, Palestine.
  • Bakri I; Department of Pathology, Al-Makassed Islamic Charitable Hospital, Jerusalem 97103, Palestine.
J Surg Case Rep ; 2024(8): rjae517, 2024 Aug.
Article en En | MEDLINE | ID: mdl-39211378
ABSTRACT
Glioblastoma multiforme (GBM) is a highly aggressive brain tumor. Individuals with neurofibromatosis type 1 (NF1) have an increased risk of developing GBM. We present a case report of a 44-year-old male with NF1 who developed GBM. NF1-associated GBM presents distinct molecular features and younger age at diagnosis compared to sporadic cases. Treatment typically follows standard protocols for GBM. Despite advancements in neuro-oncology, gaps in knowledge persist regarding NF1-associated GBM, including its prevalence, molecular mechanisms, and optimal treatment strategies. Larger studies and collaborative efforts are needed to address these gaps and enhance patient care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Surg Case Rep Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Surg Case Rep Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido