Reference Standard of Median Nerve Conduction Study in Korea.

Lee, Jae Hyun; Kim, Eunkyung; Shim, Hyung-Seok; Kang, Min-Gu; Kim, Keewon; Lee, Sang Yoon; Lee, Goo Joo; Lee, Shi-Uk; Lim, Jae-Young; Chung, Sun Gun; Oh, Byung-Mo

Lee, Jae Hyun; Kim, Eunkyung; Shim, Hyung-Seok; Kang, Min-Gu; Kim, Keewon; Lee, Sang Yoon; Lee, Goo Joo; Lee, Shi-Uk; Lim, Jae-Young; Chung, Sun Gun; Oh, Byung-Mo.

Afiliación

Lee JH; Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul, Korea.
Kim E; Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul, Korea.
Shim HS; Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Kang MG; Data Center for Korean Reference Nerve Conductions, Seoul National University Hospital, Seoul, Korea.
Kim K; National Center for Standard Reference Data, Daejeon, Korea.
Lee SY; Korea Research Institute of Standards and Science, Daejeon, Korea.
Lee GJ; Department of Rehabilitation Medicine, Daegu Workers' Compensation Hospital, Daegu, Korea.
Lee SU; Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul, Korea.
Lim JY; Data Center for Korean Reference Nerve Conductions, Seoul National University Hospital, Seoul, Korea.
Chung SG; Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul, Korea.
Oh BM; Data Center for Korean Reference Nerve Conductions, Seoul National University Hospital, Seoul, Korea.

Ann Rehabil Med ; 48(4): 259-270, 2024 Aug.

Article en En | MEDLINE | ID: mdl-39210750

ABSTRACT

ABSTRACT

OBJECTIVE:

To establish the reference standard of the median nerve conduction study (NCS) in Korea.

METHODS:

A total of 648 median motor and 602 median sensory NCSs from 349 Korean healthy volunteers were tested and analyzed prospectively. Equipment calibration, assessment of intraand inter-rater reliability, and the NCSs per se were conducted according to a predetermined protocol. A reference standard was established from uncertainty components for the following parameters the onset and peak latencies; the baseline-to-peak and peak-to-peak amplitudes; the area and duration of the negative wave; and the nerve conduction velocity. The effects of sex, age and stimulation intensity were analyzed.

RESULTS:

Each measured value of 648 median motor and 602 median sensory nerves were obtained and presented with both mean and expanded uncertainties, as well as mean and standard deviations. The cut-off values with expanded uncertainty were determined for different age and sex groups. After adjusting for anthropometric covariates, all parameters except duration were affected by age, and sex appeared to influence both duration and area. While stimulation intensity significantly affected some parameters including latencies, the effect sizes were negligible.

CONCLUSION:

We propose the median NCS reference standard using the largest Korean dataset ever available. The use of the traceable and reliable reference standard is anticipated to promote more accurate and dependable diagnosis and appropriate management of median neuropathies in Korea.

Palabras clave

Median nerve; Nerve conduction studies; Reference standards; Reference values; Uncertainty

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Ann Rehabil Med Año: 2024 Tipo del documento: Article Pais de publicación: