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Risk analysis of blood pressure changes on cardiovascular disease in Chinese population.
Xu, Lei; Wang, Kai; Yan, Tao; Li, Lehui; Miao, Yu; Tian, Zixuan; Zhang, Ru; Wang, Ya; Zhang, Chunfa; Yan, Jinli; Cao, Ning; Zhang, Nan; Zhang, Xingguang.
Afiliación
  • Xu L; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Wang K; Department of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
  • Yan T; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Li L; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Miao Y; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Tian Z; Department of Disease Control and Prevention, the First Hospital of Hohhot, Hohhot, China.
  • Zhang R; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Wang Y; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Zhang C; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Yan J; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Cao N; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Zhang N; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
  • Zhang X; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
J Clin Hypertens (Greenwich) ; 2024 Aug 29.
Article en En | MEDLINE | ID: mdl-39210580
ABSTRACT
The study aimed to assess the impact of changes in blood pressure on cardiovascular events in the Chinese population. It enrolled 33 179 Chinese participants aged ≥35 years (57.1% women) without CVD at baseline. BP status was defined according to the 2017 ACC/AHA hypertension guidelines. The type of BP change was defined as change in BP status from baseline to the end of follow-up, included stable BP <130/80, <130/80 to ≥130/80, ≥130/80 to <130/80 mm Hg, persistent BP ≥130/80 mm Hg. The hazard ratio (HR) of incident CVD by change in BP category was estimated using Cox proportional hazards and Fine-Gray models. During median follow-up of 3.17 years, 2023 CVD events occurred. Compared with BP <120/80, 120-129/<80 mm Hg at baseline (HR = 1.66, 95% CI 1.09-2.53), 130-139/80-89 mm Hg (HR = 1.35, 95% CI 0.94-1.95), and ≥140/90 mm Hg (HR = 2.46, 95% CI 1.78-3.40) were risk factors for CVD. Compared with the group with stable BP <130/80 mm Hg, the risk of CVD was 1.88 (95% CI 1.40-2.53) in the group with persistent BP ≥130/80 mm Hg and 1.40 (95% CI 1.01-1.94) in the group of BP decreased to <130/80 mm Hg. These results showed that BP 120-129/<80, 130-139/80-89, and ≥140/90 mm Hg were associated with a high risk of CVD. Over time, persistent BP ≥130/80 mm Hg increased the risk of CVD, but a return to <130/80 mm Hg from hypertension decreased the risk of CVD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Hypertens (Greenwich) Asunto de la revista: ANGIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Hypertens (Greenwich) Asunto de la revista: ANGIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos