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Association between biomass exposure and COPD occurrence in Fez, Morocco: results from the BOLD study.
E L Harch, Ibtissam; Garcia-Larsen, Vanessa; Benmaamar, Soumaya; Nejjari, Chakib; E L Biaze, Mohammed; Benjelloun, Mohamed Chakib; Rhazi, Karima E L.
Afiliación
  • E L Harch I; Laboratory of Epidemiology, Clinical Research and Community Health, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fez, Morocco ibtissam.elharch@usmba.ac.ma.
  • Garcia-Larsen V; Epidemiology and Research in Health Sciences (ERESS) Research Laboratory, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
  • Benmaamar S; International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Nejjari C; Laboratory of Epidemiology, Clinical Research and Community Health, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
  • E L Biaze M; Epidemiology and Research in Health Sciences (ERESS) Research Laboratory, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
  • Benjelloun MC; Laboratory of Epidemiology, Clinical Research and Community Health, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
  • Rhazi KEL; Euromed Research Center, Euromed University of Fez, Euro-Mediterranean University of Fez, Fez, Morocco.
BMJ Open Respir Res ; 11(1)2024 Aug 28.
Article en En | MEDLINE | ID: mdl-39209349
ABSTRACT

OBJECTIVE:

To investigate the association between biomass exposure and chronic obstructive pulmonary disease (COPD) in a representative sample of adults from the Moroccan population

METHODS:

A cross-sectional study was conducted in Fez as part of the Burden of Obstructive Lung Disease (BOLD) study, which included apparently healthy subjects aged 40 years and above. Biomass exposure was defined as self-report use of various biomass types for heating or cooking. The Wood Heating Exposure Index, and the Cooking Biomass Exposure Index were used to assess biomass exposure. Participants underwent post-bronchodilator spirometry and COPD was defined as having a forced expiratory volume in 1 s/forced vital capacity ratio <0.7. Descriptive, univariate and multivariable statistical analyses adjusting for potential confounders including age, sex, smoking, education level, Mokken scale (wealth index) and occupational dust exposure were performed for the general population and separately for men and women.

RESULTS:

A total of 760 subjects were included, comprising 350 men and 410 women. In the multivariable analyses, we found a statistically significant association between a higher Wood Heating Exposure Index and COPD in men (adjusted OR=3.8; 95% CI 1.4 to 10.4). While for women, a high Cooking Biomass Exposure Index was the main factor potentially linked to the increased risk of COPD (adjusted OR=7.2; 95% CI 1.7 to 30.0).

CONCLUSION:

This study suggests that biomass exposure is a significant risk factor for COPD development in both men and women, independently of the smoking status which is known as its main risk factor.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomasa / Culinaria / Enfermedad Pulmonar Obstructiva Crónica Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: BMJ Open Respir Res Año: 2024 Tipo del documento: Article País de afiliación: Marruecos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomasa / Culinaria / Enfermedad Pulmonar Obstructiva Crónica Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: BMJ Open Respir Res Año: 2024 Tipo del documento: Article País de afiliación: Marruecos Pais de publicación: Reino Unido