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Potential of Photodynamic Therapy as a Minimally Invasive Treatment for Oral Verrucous Carcinoma.
Li, Chen; Wang, Dandan; Ding, Jian.
Afiliación
  • Li C; Department of Oral Mucosa Disease & Oral Emergency, School and Hospital of Stomatology, Jilin University, Changchun, China. Electronic address: lichen@jlu.edu.cn.
  • Wang D; Key Laboratory of Tooth Development and Bone Remodeling of Jilin Province, School and Hospital of Stomatology, Jilin University, Changchun, China; Department of Oral Pathology, School and Hospital of Stomatology, Jilin University, Changchun, China.
  • Ding J; Electrodiagnosis Department, Jilin FAW General Hospital, Jilin University, Changchun, China.
Photodiagnosis Photodyn Ther ; : 104320, 2024 Aug 27.
Article en En | MEDLINE | ID: mdl-39208921
ABSTRACT
Oral verrucous carcinoma (OVC) and proliferative verrucous leukoplakia (PVL) share similar histological characteristics and may have a common origin. When they appear simultaneously, the risk of malignant transformation in PVL increases. In elderly patients with both conditions, a safe, effective, simple, and minimally invasive treatment is preferable. Photodynamic therapy (PDT), a non-invasive treatment, utilizes specific wavelengths of light to activate photosensitizers, generating reactive oxygen species that selectively target malignant tissues with cytotoxic effects. This case report describes an elderly patient with coexisting extensive leukoplakia, PVL, and OVC, who achieved complete remission with no recurrence at 10 months following PDT. The treatment resulted in a satisfactory clinical outcome, preserving both the appearance and function of the oral cavity.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Photodiagnosis Photodyn Ther Asunto de la revista: DIAGNOSTICO POR IMAGEM / TERAPEUTICA Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Photodiagnosis Photodyn Ther Asunto de la revista: DIAGNOSTICO POR IMAGEM / TERAPEUTICA Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos