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Evaluation of the psychometric properties of the UBACC questionnaire in a multi-country psychiatric study in Africa.
Kipkemoi, Patricia; Mufford, Mary S; Akena, Dickens; Alemayehu, Melkam; Atwoli, Lukoye; Chibnik, Lori B; Gelaye, Bizu; Gichuru, Stella; Kariuki, Symon M; Koenen, Karestan C; Kwobah, Edith; Kyebuzibwa, Joseph; Mwema, Rehema M; Newton, Charles R J C; Pretorius, Adele; Stein, Dan J; Stevenson, Anne; Stroud, Rocky E; Teferra, Solomon; Zingela, Zukiswa; Post, Kristianna; Korte, Kristina J.
Afiliación
  • Kipkemoi P; Neuroscience Unit, KEMRI-Wellcome Trust Research Program, Kenya; Global Initiative for Neuropsychiatric Genetics Education in Research (GINGER) Program, Harvard T.H. Chan School of Public Health and the Stanley Center for Psychiatric Research at the Broad Institute of Harvard and MIT, USA; Complex T
  • Mufford MS; Global Initiative for Neuropsychiatric Genetics Education in Research (GINGER) Program, Harvard T.H. Chan School of Public Health and the Stanley Center for Psychiatric Research at the Broad Institute of Harvard and MIT, USA; SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psy
  • Akena D; Department of Psychiatry, School of Medicine, College of Health Sciences, Makerere University, Uganda.
  • Alemayehu M; Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia.
  • Atwoli L; Department of Mental Health, School of Medicine, Moi University College of Health Sciences, Kenya; Brain and Mind Institute and Department of Medicine, Medical College East Africa, the Aga Khan University, Kenya.
  • Chibnik LB; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, USA.
  • Gelaye B; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, USA; Department of Social and Behavioral Sciences, Harvard
  • Gichuru S; Department of Mental Health, Moi Teaching and Referral Hospital, Eldoret, Kenya.
  • Kariuki SM; Neuroscience Unit, KEMRI-Wellcome Trust Research Program, Kenya; Department of Psychiatry, University of Oxford, UK.
  • Koenen KC; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, USA; Department of Psychiatry, Massachusetts General Hospita
  • Kwobah E; Department of Mental Health, Moi Teaching and Referral Hospital, Eldoret, Kenya.
  • Kyebuzibwa J; Department of Psychiatry, School of Medicine, College of Health Sciences, Makerere University, Uganda.
  • Mwema RM; Neuroscience Unit, KEMRI-Wellcome Trust Research Program, Kenya.
  • Newton CRJC; Neuroscience Unit, KEMRI-Wellcome Trust Research Program, Kenya; Department of Psychiatry, University of Oxford, UK.
  • Pretorius A; SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, South Africa.
  • Stein DJ; SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, South Africa.
  • Stevenson A; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA; Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa.
  • Stroud RE; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA.
  • Teferra S; Department of Psychiatry, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia.
  • Zingela Z; Executive Dean's Office, Faculty of Health Sciences, Nelson Mandela University, South Africa.
  • Post K; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, USA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA.
  • Korte KJ; Department of Epidemiology, Harvard T. H. Chan School of Public Health, USA; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, USA.
Compr Psychiatry ; 135: 152526, 2024 Aug 26.
Article en En | MEDLINE | ID: mdl-39208558
ABSTRACT

BACKGROUND:

The University of California, San Diego Brief Assessment of Capacity to Consent (UBACC) is a tool to assess the capacity of participants to consent in psychiatric research. However, little is known about the psychometric properties in low and middle-income countries. This study aimed to examine the psychometric properties of the UBACC.

METHODS:

We examined the reliability, latent factor structure, and item response of the first attempt of the UBACC items in a sample of 32,208 adults (16,467 individuals with psychosis and 15,741 controls) in Ethiopia, Kenya, South Africa, and Uganda; exploring these properties in the full sample and stratified by country, diagnostic status, sex, and ethnolinguistic language groups.

RESULTS:

Exploratory factor analysis (EFA) suggested a two-factor model for the overall sample. However, a three-factor model was more appropriate when examining the latent structure across country, language, and sex. Confirmatory factor analyses (CFA) revealed an adequately fitting three-factor model for the full sample and across country, sex, and language. A two-factor model, however, was more appropriate for English and Amharic languages. Across all groups, the internal consistency of the UBACC was low, indicating below-threshold reliability (Cronbach's α (95 % CI = 0.58 (0.57-0.59). Using a multidimensional item-response theory framework for the full sample revealed that UBACC item 8, measuring understanding of the benefits of study participation, was the most discriminating item. Many of the other items had below-threshold discriminating characteristics.

CONCLUSION:

EFA and CFA converged towards a two and three-dimensional structure for the UBACC, in line with the developers of the original scale. The differences in properties between populations and language groups, low internal consistency, and below-threshold item functioning suggest that investigations into the cultural and linguistic nuances are still warranted. Understanding the utility of consent tools, such as the UBACC, in underrepresented populations will be a part of the larger process which ensures that research participants are adequately protected.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Compr Psychiatry Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Compr Psychiatry Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos