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Adherence to Short-Duration Treatment (3HP) for Latent Tuberculosis among International Migrants in Manaus, Amazonas: Evaluation of the Efficacy of Different Treatment Modalities.
Alves, Yan Mathias; Berra, Thaís Zamboni; Jezus, Sonia Vivian de; Araújo, Vânia Maria Silva; Pinheiro, Jair Dos Santos; Assis, Lara Bezerra de Oliveira de; Canelonez, Marvis; Sacramento, Daniel Souza; Perez, Freddy; Maciel, Ethel Leonor Noia; Arcêncio, Ricardo Alexandre.
Afiliación
  • Alves YM; Department of Maternal-Infant and Public Health Nursing, Ribeirão Preto College of Nursing, University of São Paulo, Ribeirão Preto 14040-902, Sao Paulo, Brazil.
  • Berra TZ; Brazilian Tuberculosis Research Network (REDE-TB), Rio de Janeiro 21941-904, Rio de Janeiro, Brazil.
  • Jezus SV; Department of Maternal-Infant and Public Health Nursing, Ribeirão Preto College of Nursing, University of São Paulo, Ribeirão Preto 14040-902, Sao Paulo, Brazil.
  • Araújo VMS; Brazilian Tuberculosis Research Network (REDE-TB), Rio de Janeiro 21941-904, Rio de Janeiro, Brazil.
  • Pinheiro JDS; Sinop Campus, Federal University of Mato Grosso (UFMT), Sinop 78550-728, Mato Grosso, Brazil.
  • Assis LBO; Brazilian Tuberculosis Research Network (REDE-TB), Rio de Janeiro 21941-904, Rio de Janeiro, Brazil.
  • Canelonez M; State Tuberculosis Control Program of Amazonas, Manaus 69093-018, Amazonas, Brazil.
  • Sacramento DS; State Tuberculosis Control Program of Amazonas, Manaus 69093-018, Amazonas, Brazil.
  • Perez F; State Tuberculosis Control Program of Amazonas, Manaus 69093-018, Amazonas, Brazil.
  • Maciel ELN; Municipal Tuberculosis Control Program, Manaus 69049-110, Amazonas, Brazil.
  • Arcêncio RA; Communicable Diseases Prevention, Control, and Elimination and Environmental Determinants of Health Department, Pan American Health Organization, Washington, DC 20037, USA.
Microorganisms ; 12(8)2024 Aug 09.
Article en En | MEDLINE | ID: mdl-39203470
ABSTRACT
Migration, a multifaceted phenomenon, has a significant impact on health. Migrants perform similar movement patterns within their country of origin, in transit, and in the country of destination, thus making it difficult to monitor TB treatment throughout the journey. The objective was to compare the effectiveness of different treatment modalities in adherence to the short-term regimen for LTBI (3HP) among international migrants and refugees. This is a quasi-experimental study conducted in Manaus-AM. The study population was made up of international migrants. The certification and monitoring of medication intake employed three strategies self-administration (SA), directly observed conventional therapy (DOT), and Video Telemonitoring System for Tuberculosis Treatment (VDOT). The VDOT group and SA group exhibited the lowest rate of treatment dropout or interruption at 16.1%, followed by the DOT group at 23.1%. The results suggest that the most effective strategy for ensuring adherence among migrants and refugees was VDOT (OR_adj 0.26; CI 0.7-0.94), suggesting that migrants may be more likely to adhere to and complete their treatment. The results show that relying on different treatment strategies, adapted to the individuals' needs and risk factors, is a viable and effective way of providing person-centered TB care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Microorganisms Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Microorganisms Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza