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Advances in the Management of Localized Scleroderma: A Systematic Review of Laser Therapy and Injectable Filler Approaches.
Cassalia, Fortunato; Federico, Serena; Danese, Andrea; Franceschin, Ludovica; Amato, Simone; Gratteri, Francesco; Battilotti, Chiara; Caroppo, Francesca; Zappia, Elena; Bennardo, Luigi; Belloni Fortina, Anna; Nisticò, Steven Paul.
Afiliación
  • Cassalia F; Unit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.
  • Federico S; Department of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
  • Danese A; Unit of Dermatology, Department of Integrated Medical and General Activity, University of Verona, 37100 Verona, Italy.
  • Franceschin L; Unit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.
  • Amato S; Dermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.
  • Gratteri F; Unit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.
  • Battilotti C; Dermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.
  • Caroppo F; Unit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.
  • Zappia E; Department of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
  • Bennardo L; Department of Medical Sciences, University of Turin, 10126 Turin, Italy.
  • Belloni Fortina A; Department of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
  • Nisticò SP; Unit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.
J Pers Med ; 14(8)2024 Aug 17.
Article en En | MEDLINE | ID: mdl-39202063
ABSTRACT
Localized scleroderma (LS), commonly known as morphea, presents a significant clinical challenge due to its chronic, inflammatory nature affecting the skin and potentially underlying tissues. This systematic review explores the innovative approach of combining laser therapy and injectable fillers, specifically hyaluronic acid, for the treatment of LS. We conducted a comprehensive literature review following PRISMA guidelines, examining articles from MEDLINE/PubMed to assess the combined efficacy of these treatments in improving both esthetic and functional outcomes for LS patients. The search yielded 64 articles, with six selected for in-depth analysis for a total of nine patients, covering a range of patient demographics and treatment types. Our review highlights cases where fractional CO2 laser therapy promoted long-term tissue remodeling and instances where hyaluronic acid fillers effectively addressed skin atrophy and volume loss, enhancing both immediate and long-lasting esthetic improvements. The synergy between these treatments suggests a promising dual approach, aiming to maximize esthetic outcomes and to improve the quality of life for LS patients. This review underscores the necessity of further research to establish a comprehensive, evidence-based clinical pathway integrating both treatments for managing LS, thereby enhancing patient satisfaction and addressing the multifaceted nature of this challenging dermatological condition.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pers Med Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pers Med Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza