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Impact of Prescription Opioid Detoxification on Quality of Life and Pain Levels.
Laubner Sakalauskiene, Gabija; Straznickaite, Indre; Miskinyte, Sigute; Zdanavicius, Linas; Sipylaite, Jurate; Badaras, Robertas.
Afiliación
  • Laubner Sakalauskiene G; Clinic of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
  • Straznickaite I; Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
  • Miskinyte S; Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
  • Zdanavicius L; Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
  • Sipylaite J; Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
  • Badaras R; Clinic of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania.
Clin Pract ; 14(4): 1529-1537, 2024 Aug 08.
Article en En | MEDLINE | ID: mdl-39194927
ABSTRACT

PURPOSE:

The aim of this study was to examine the impact of detoxification from prescription opioids on the quality of life (QoL) and pain levels among patients reliant on these medications for chronic pain management.

OBJECTIVE:

Long-term use of opioids for pain management may lead to a range of adverse effects, including tolerance, dependence, significant societal costs, and a decline in overall quality of life (QoL). Despite these challenges, there is a limited amount of research focusing on the effects of detoxification and its impact on the QoL for patients with chronic pain tolerant to prescription opioids.

METHODS:

This prospective study included 45 patients who underwent elective detoxification from prescription opioids. Prescription opioids were discontinued during the detoxification treatment in 44 of the 45 cases. QoL was monitored using SF-36v2™ questionnaires administered before detoxification, on the day of discharge, and at least six months after detoxification. Pain levels were assessed using Visual Analogue Scale (VAS) scores before and after the detoxification process.

RESULTS:

The study was fully completed by 30 patients. At the third SF-36v2™ evaluation, 25 out of 30 patients (83.3%) reported the detoxification treatment as beneficial to their overall health status compared to that before the treatment, and SF-36v2™ questionnaires after detoxification were significantly higher than before the treatment (p < 0.001). A decreased pain level right after the detoxification was reported by 44 of the 45 patients (97.7%), with a significant average reduction of 4.51 points observed (p < 0.001).

CONCLUSIONS:

The observed enhancement in QoL, significant reduction in pain, and cessation of opioid use in most patients with chronic pain tolerant to prescription opioids following opioid detoxification indicate that this method of treatment can be safely and effectively administered and must be considered for chronic pain patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Pract Año: 2024 Tipo del documento: Article País de afiliación: Lituania Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Pract Año: 2024 Tipo del documento: Article País de afiliación: Lituania Pais de publicación: Suiza