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Cuttlefish Bone-Derived Calcium Phosphate Bioceramics Have Enhanced Osteogenic Properties.
Pang, Boqi; Xian, Jiaru; Chen, Jiajun; Ng, Liqi; Li, Mengting; Zhao, Guangchun; E, Yixun; Wang, Xiaorui; Cao, Xiaxin; Zhang, Changze; Zhang, Mingjing; Liu, Chaozong.
Afiliación
  • Pang B; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Xian J; Institute of Orthopaedic & Musculoskeletal Science, University College London, Royal National Orthopaedic Hospital, London HA7 4LP, UK.
  • Chen J; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Ng L; Institute of Orthopaedic & Musculoskeletal Science, University College London, Royal National Orthopaedic Hospital, London HA7 4LP, UK.
  • Li M; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Zhao G; Institute of Orthopaedic & Musculoskeletal Science, University College London, Royal National Orthopaedic Hospital, London HA7 4LP, UK.
  • E Y; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Wang X; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Cao X; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Zhang C; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Zhang M; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
  • Liu C; Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China.
J Funct Biomater ; 15(8)2024 Jul 29.
Article en En | MEDLINE | ID: mdl-39194650
ABSTRACT
Cuttlefish bones are byproducts of cuttlefish processing and are readily available in the marine food industry. In this study, calcium phosphate bioceramics were prepared from cuttlefish bones using a two-stage hydrothermal calcination process. The results indicated that all bioceramics derived from cuttlefish bones had a higher degradation capacity, better bone-like apatite formation ability, and higher degree of osteogenic differentiation than commercially available hydroxyapatite. Notably, ß-tricalcium phosphate, which had the highest degree of Ca2+ and Sr2+ dissolution among the bioceramics extracted, can significantly upregulate osteogenic markers (alkaline phosphatase, osteocalcin) and stimulate bone matrix mineralization. Thus, it is a promising bioceramic material for applications in bone regeneration.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Funct Biomater Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Funct Biomater Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza