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Comparison of the effects of high-flow nasal cannula and bilevel positive airway pressure treatments as respiratory physiotherapy interventions for children with asthma exacerbation: a randomized clinical trial.
David, Maisi Muniz Cabral; Gomes, Evelim Leal de Freitas Dantas; Cavassini, Carla Lima Feitoza; Luiz, Josiane Germano; Costa, Dirceu.
Afiliación
  • David MMC; Post graduation program Science Rehabilitation, Universidade Nove de Julho, São Paulo, SP, Brazil.
  • Gomes ELFD; Post graduation program Science Rehabilitation, Universidade de São Paulo, São Paulo, SP, Brazil.
  • Cavassini CLF; Post graduation program Science Rehabilitation, Universidade Nove de Julho, São Paulo, SP, Brazil.
  • Luiz JG; Post graduation program Science Rehabilitation, Universidade Nove de Julho, São Paulo, SP, Brazil.
  • Costa D; Post graduation program Science Rehabilitation, Universidade Nove de Julho, São Paulo, SP, Brazil.
Einstein (Sao Paulo) ; 22: eAO0588, 2024.
Article en En | MEDLINE | ID: mdl-39194097
ABSTRACT

OBJECTIVE:

A high-flow nasal cannula is a practical and safe instrument that can be used for children with asthma exacerbation and promotes beneficial outcomes such as improved asthma severity scores and reduced hospitalization durations, salbutamol use, and oxygen use. To evaluate and compare the efficacy of high-flow nasal cannula treatment and that of bilevel positive airway pressure treatment as respiratory physiotherapy interventions for pediatric patients who are hospitalized because of asthma exacerbation.

METHODS:

During a randomized clinical trial, treatment was performed using a high-flow nasal cannula and bilevel positive airway pressure for hospitalized children with asthma. After randomization, data regarding lung function, vital signs, and severity scores (pulmonary index, pediatric asthma severity, and pediatric asthma scores) were collected.

RESULTS:

Fifty patients were included in this study (25 in the Bilevel Group and 25 in the high-flow nasal cannula group). After 45 minutes of therapy, an improvement in the forced expiratory volume in 1 second was observed. The high-flow nasal cannula group required fewer days of oxygen (O2) use, used fewer bronchodilators (number of salbutamol puffs), and required shorter hospitalization periods than the Bilevel Group (6.1±1.9 versus 4.3±1.3 days; 95% confidence interval, -5.0 to -0.6).

CONCLUSION:

A high-flow nasal cannula is a viable option for the treatment of asthma exacerbation because it can reduce the hospitalization period and the need for O2 and bronchodilators. Additionally, it is a safe and comfortable treatment modality that is as effective as bilevel positive airway pressure.ClinicalTrials.gov Identifier NCT04033666.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Cánula Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Einstein (Sao Paulo) Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Cánula Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Einstein (Sao Paulo) Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil