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Navigating the transition: a multidisciplinary approach to inflammatory bowel disease in children.
Raffaele, A; Ferlini, C M; Fusi, G; Lenti, M V; Cereda, E; Caimmi, S M E; Bertozzi, M; Riccipetitoni, G.
Afiliación
  • Raffaele A; Department of Clinical, Surgical, Diagnostics and Pediatric Sciences, University of Pavia, Pavia, Italy.
  • Ferlini CM; Pediatric Surgery Unit, Department of Maternal and Child Health, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Fusi G; Pediatric Surgery Unit, Department of Maternal and Child Health, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Lenti MV; Pediatric Surgery Unit, Department of Maternal and Child Health, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Cereda E; Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
  • Caimmi SME; Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
  • Bertozzi M; Clinical Nutrition and Dietetics Unit, Department of Oncology and Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Riccipetitoni G; Pediatrics Unit, Department of Maternal and Child Health, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Pediatr Surg Int ; 40(1): 245, 2024 Aug 27.
Article en En | MEDLINE | ID: mdl-39192007
ABSTRACT

PURPOSE:

A multidisciplinary approach to Inflammatory Bowel Disease (IBD) has recently demonstrated a positive impact in pediatric patients, reducing dropout rates and facilitating the transition to adult care. Our study aims to evaluate how this approach influences disease activity, dropout rates, and transition.

METHODS:

We conducted a longitudinal observational study including all patients diagnosed with IBD during pediatric-adolescent age, with a minimum follow-up period of 12 months. For each patient, endpoints included therapeutic approach, need for surgery and transition features.

RESULTS:

We included 19 patients 13 with Ulcerative Colitis (UC) and 6 with Crohn's disease (CD). Most patients required multiple lines of therapy, with over 50% in both groups receiving biological drugs. Compliance was good, with a single dropout in each group (10, 5%). The need for surgery was significantly higher in the CD group compared to the UC group (16% vs. 7.7%, p < 0.01). Mean age at transition was significantly higher in the UC group compared to the CD group (19.2 ± 0.7 years SD vs. 18.3 ± 0.6 years SD, p < 0.05).

CONCLUSIONS:

In our experience, the multidisciplinary approach to IBD in transition-age patients appears effective in achieving clinical remission, offering the potential to reduce therapeutic dropouts.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Transición a la Atención de Adultos Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Pediatr Surg Int Asunto de la revista: PEDIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Transición a la Atención de Adultos Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: Pediatr Surg Int Asunto de la revista: PEDIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Alemania