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Pediatric cancer screening in hereditary gastrointestinal cancer risk syndromes: An update from the AACR Childhood Cancer Predisposition Working Group.
MacFarland, Suzanne P; Becktell, Kerri; Schneider, Kami Wolfe; Kuiper, Roland P; Lesmana, Harry; Meade, Julia; Nichols, Kim E; Porter, Christopher C; Savage, Sharon A; Schultz, Kris Ann; Scott, Hamish; States, Lisa; Tabori, Uri; Tamura, Chieko; Tomlinson, Gail; Zelley, Kristin; Durno, Carol; Bauer, Andrew; Plon, Sharon E.
Afiliación
  • MacFarland SP; Children's Hospital of Philadelphia, Philadephia, PA, United States.
  • Becktell K; Medical College of Wisconsin, Milwaukee, WI, United States.
  • Schneider KW; University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
  • Kuiper RP; Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands.
  • Lesmana H; Cleveland Clinic, Cleveland, United States.
  • Meade J; University of Pittsburgh, Pittsburgh, PA, United States.
  • Nichols KE; St. Jude Children's Research Hospital, Memphis, United States.
  • Porter CC; Emory University, Atlanta, GA, United States.
  • Savage SA; National Cancer Institute, Bethesda, United States.
  • Schultz KA; Children's Minnesota, Minneapolis, MN, United States.
  • Scott H; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia.
  • States L; Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Tabori U; Hospital for Sick Children, Toronto, Ontario, Canada.
  • Tamura C; FMC Tokyo Clinic, Tokyo, Japan.
  • Tomlinson G; The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States.
  • Zelley K; Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Durno C; Hospital for Sick Children, Toronto, Ontario, Canada.
  • Bauer A; Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Plon SE; Baylor College of Medicine, Houston, TX, United States.
Clin Cancer Res ; 2024 Aug 27.
Article en En | MEDLINE | ID: mdl-39190470
ABSTRACT
Gastrointestinal (GI) polyposis and cancer in pediatric patients is frequently due to an underlying hereditary cancer risk syndrome requiring ongoing cancer screening. Identification of at-risk patients through family history, clinical features of syndrome, or symptom onset ensures appropriate cancer risk assessment and management in childhood and beyond. In this 2024 perspective, we outline updates to the hereditary GI cancer screening guidelines first published by the American Association of Cancer Research Pediatric Cancer Predisposition Workshop in 2017.1 These guidelines consider existing recommendations by pediatric and adult gastroenterology consortia to ensure alignment with gastroenterology practices in managing polyposis conditions. We specifically address the recommendations for pediatric screening in familial adenomatous polyposis, Peutz-Jeghers syndrome, and juvenile polyposis syndrome. Further, we emphasize the importance of multidisciplinary care and partnership with gastroenterology, as it is crucial in management of children and families with these conditions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos