Your browser doesn't support javascript.
loading
Prognostic significance of exercise stress echocardiography using two and three diastolic variable approaches.
Omar, Alaa Mabrouk Salem; Konje, Swiri; Monuz, Alba; Alam, Loba; Ghandi, Kruti; Moras, Errol; Miester, David; Pena, Maria; Perez-Lizardo, Christopher; Kim, Gahee; Elias, Joseph; Argulian, Edgar.
Afiliación
  • Omar AMS; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Konje S; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Monuz A; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Alam L; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ghandi K; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Moras E; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Miester D; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Pena M; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Perez-Lizardo C; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kim G; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Elias J; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Argulian E; Department of Cardiology, Mount Sinai Morningside, New York, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: Edgar.Argulian@mountsinai.org.
Int J Cardiol ; 416: 132483, 2024 Dec 01.
Article en En | MEDLINE | ID: mdl-39187072
ABSTRACT

BACKGROUND:

The prognostic utility of comprehensive, guideline-defined assessment of diastolic measures during routine exercise echocardiography remains unclear.

OBJECTIVES:

The purpose of the study was to pragmatically assess the prognostic role of obtainable Doppler-derived diastolic variables during treadmill exercise echocardiography.

METHODS:

In this retrospective study, the authors included 1910 patients undergoing exercise echocardiography. The guideline-defined diastolic measures included resting septal e' velocity, post-exercise E/e' ratio and post-exercise tricuspid regurgitant jet velocity. Since tricuspid regurgitant jet velocity is not routinely obtainable, the authors examined 2 approaches 2 variable approach using only resting septal e' velocity and post-exercise E/e' ratio and 3 variable approach with all diastolic variables.

RESULTS:

The mean age of study subjects was 57.6 ± 16 years and 1068 (56 %) were women. The tricuspid jet velocity was not reliably obtained in 501(26 %) of patients. All 3 diastolic variables were associated with the hard outcomes (mortality, acute coronary syndrome, cardiac hospitalization), soft outcomes (subsequent revascularization and cardiac testing), as well as the composite outcome. In the 2-variable approach, the presence of 2 abnormal variables was associated with a worse composite outcome. In the 3 variable approach, the presence of 2 or 3 abnormal variables was associated with a worse composite outcome. The associations persisted after multivariable adjustment and in the propensity matched subgroups.

CONCLUSIONS:

Guideline-defined diastolic variables during treadmill exercise echocardiography offer prognostic utility when used in combination, especially if all 3 variables are obtainable.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ecocardiografía de Estrés / Diástole Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ecocardiografía de Estrés / Diástole Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos