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Semi-automated vertex placement for lattice radiotherapy and dosimetric verification using 3D polymer gel dosimetry.
Kunkyab, Tenzin; Magliari, Anthony; Jirasek, Andrew; Mou, Benjamin; Hyde, Derek.
Afiliación
  • Kunkyab T; Department of Computer Science, Mathematics, Physics and Statistics, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
  • Magliari A; BC Cancer, Kelowna, British Columbia, Canada.
  • Jirasek A; Varian Medical Systems, Palo Alto, California, USA.
  • Mou B; Department of Computer Science, Mathematics, Physics and Statistics, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
  • Hyde D; BC Cancer, Kelowna, British Columbia, Canada.
J Appl Clin Med Phys ; : e14489, 2024 Aug 26.
Article en En | MEDLINE | ID: mdl-39186819
ABSTRACT

PURPOSE:

To evaluate the feasibility of an open-source, semi-automated, and reproducible vertex placement tool to improve the efficiency of lattice radiotherapy (LRT) planning. We used polymer gel dosimetry with a Cone Beam CT (CBCT) readout to commission this LRT technique. MATERIAL AND

METHODS:

We generated a volumetric modulated arc therapy (VMAT)-based LRT plan on a 2 L NIPAM polymer gel dosimeter using our Eclipse Acuros version 15.6 AcurosXB beam model, and also recalculated the plan with a pre-clinical Acuros v18.0 dose calculation algorithm with the enhanced leaf modelling (ELM). With the assistance of the MAAS-SFRThelper software, a lattice vertex diameter of 1.5 cm and center-to-center spacing of 3 cm were used to place the spheres in a hexagonal, closed packed structure. The verification plan included four gantry arcs with 15°, 345°, 75°, 105° collimator angles. The spheres were prescribed 20 Gy to 50% of their combined volume. The 6 MV Flattening Filter Free beam energy was used to deliver the verification plan. The dosimetric accuracy of the LRT delivery was evaluated with 1D dose profiles, 2D isodose maps, and a 3D global gamma analysis.

RESULTS:

Qualitative comparisons between the 1D dose profiles of the Eclipse plan and measured gel showed good consistency at the prescription dose mark. The average diameter measured 13.3 ± 0.2 mm (gel for v15.6), 12.6 mm (v15.6 plan), 13.1 ± 0.2 mm (gel for v18.0), and 12.3 mm (v18.0 plan). 3D gamma analysis showed that all gamma pass percent were > 95% except at 1% and 2% at the 1 mm distance to agreement criteria.

CONCLUSION:

This study presents a novel application of gel dosimetry in verifying the dosimetric accuracy of LRT, achieving excellent 3D gamma results. The treatment planning was facilitated by publicly available software that automatically placed the vertices for consistency and efficiency.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Appl Clin Med Phys Asunto de la revista: BIOFISICA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Appl Clin Med Phys Asunto de la revista: BIOFISICA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos