Flynotyper 2.0: An updated tool for rapid quantitative assessment of Drosophila eye phenotypes.
bioRxiv
; 2024 Aug 16.
Article
en En
| MEDLINE
| ID: mdl-39185196
ABSTRACT
About two-thirds of the genes in the Drosophila melanogaster genome are also involved in its eye development, making the Drosophila eye an ideal system for genetic studies. We previously developed Flynotyper, a software that uses image processing operations to identify and quantify the degree of roughness by measuring disorderliness of ommatidial arrangement in the fly eye. This software has enabled researchers to quantify morphological defects of thousands of eye images caused by genetic perturbations. Here, we present Flynotyper 2.0, a software that has an updated computer vision library, improved performance, and a streamlined pipeline for high-throughput analysis of multiple eye images. We also tested several batches of Drosophila eye images to ensure robustness and reproducibility of the updated Flynotyper 2.0 software. Availability and implementation The source code for Flynotyper 2.0 can be downloaded and installed from https//github.com/girirajanlab/flynotyper-desktop-application.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
BioRxiv
Año:
2024
Tipo del documento:
Article
País de afiliación:
Panamá
Pais de publicación:
Estados Unidos