Your browser doesn't support javascript.
loading
In vivo mosquito repellency effect of citronella (Cymbopogon nardus (L.) Rendle) essential oil bath bomb formulation in dogs.
Uopasai, Suwit; Senaphan, Ketmanee; Borlace, Glenn Neville; Thongkham, Eakachai; Aiemsaard, Jareerat.
Afiliación
  • Uopasai S; Division of Anatomy, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
  • Senaphan K; Division of Physiology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
  • Borlace GN; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
  • Thongkham E; Division of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
  • Aiemsaard J; Division of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Vet World ; 17(7): 1538-1544, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39185036
ABSTRACT
Background and

Aim:

Mosquitoes carry numerous diseases of medical and veterinary significance. While citronella essential oil is safe as a mosquito repellent, extensive research does not document its ability to deter mosquitoes from animals. This study assessed the citronella essential oil bath bomb's ability to repel Culex quinquefasciatus mosquitoes in dogs. Materials and

Methods:

Citronella essential oil's chemical composition was analyzed using gas chromatography-mass spectrometry (GC-MS). Through freeze-thaw testing, a bath bomb formulation containing 6% w/w citronella essential oil was assessed for its physical and chemical stability. Thirty-two healthy client-owned mixed-breed dogs were employed to test the mosquito-repellency effects of citronella essential oil (treatment group) and olive oil (control group) bath bomb formulations. Bath bombs were tested for irritation effects on animal skin for 15-day post-application.

Results:

Thirty-six compounds were identified through GC-MS, with citronellal (23.38%), δ-cadinene (12.25%), and geraniol (9.09%) being the most prevalent constituents. The bath bomb maintained its original physical properties after undergoing six freeze-thawing cycles and retained over 90% of its citronella essential oil. About 100%, 69.28%, and 65.58% mosquito repellency were displayed by the citronella essential oil bath bomb at 3 h, 6 h, and 8 h, respectively. None of the test animals exhibited skin irritation during the study.

Conclusion:

The citronella bath bomb effectively repelled C. quinquefasciatus in dogs without irritating their skin. The formulation's physical and chemical stability is demonstrated by the results of freeze-thaw stability testing. Further studies should be conducted to evaluate the repelling activity against other mosquito species.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vet World Año: 2024 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vet World Año: 2024 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: India