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Multidisciplinary team discussion based on etiological treatment improves refractory chronic cough outcomes.
Lu, Yicong; Huang, Wanting; Fang, Danruo; Wang, Huijie; Guo, Jiangying; Li, Na; Wang, Xuefen; Chen, Miaoyan; Chen, Jia; Huang, Huaqiong.
Afiliación
  • Lu Y; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China.
  • Huang W; Department of Otorhinolaryngology, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China.
  • Fang D; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China.
  • Wang H; Tuberculosis Department, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208# Huancheng east Road, Hangzhou, Zhejiang, 310006, China.
  • Guo J; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China.
  • Li N; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China.
  • Wang X; Department of Respiratory Medicine, The First Affiliated Hospital of Zhejiang University School of Medicine, 79# Qingchun Road, Hangzhou, Zhejiang, 310003, China.
  • Chen M; Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China. Electronic address: chenmiaoyan8@zju.edu.cn.
  • Chen J; Department of Otorhinolaryngology, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China. Electronic address: chenjia212c@zju.edu.cn.
  • Huang H; Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, 88# Jiefang Road, Hangzhou, Zhejiang, 310009, China. Electronic address: zr_hhq@zju.edu.cn.
Respir Investig ; 62(6): 942-950, 2024 Aug 24.
Article en En | MEDLINE | ID: mdl-39182399
ABSTRACT

BACKGROUND:

Refractory chronic cough (RCC) causes significant impairments in the life quality of patients. Further research into the identification of etiologies and development of the treatment schedules for RCC is needed. PATIENTS AND

METHODS:

We established an multidisciplinary team (MDT) clinic, by integrating respiratory medicine, otorhinolaryngology, and gastroenterology departments, to investigate cough etiologies and the effectiveness of treatment. The therapeutic effect was assessed quantitatively using the Cough Visual Analog Scales (VAS), Leicester Cough Questionnaire (LCQ), and Reflux Symptoms Index (RSI) scores.

RESULTS:

In total, 213 patients attending the MDT outpatient clinic were examined, and 115 patients with RCC were included for analysis. The RCC diagnosis rate among the outpatient was 88.7%. Common causes of RCC included gastroesophageal reflux cough (63.5%), upper airway cough syndrome (UACS) (43.5%), and cough variant asthma (CVA) (14.8%). After an average treatment period of 2.17 ± 1.06 weeks (wk), 73.9% of the patients had partial cough remission, and 6.1% had complete cough remission. The cough VAS score before and after treatment was 6.11 ± 2.02 vs. 3.66 ± 2.22 (P < 0.05), respectively; LCQ total score before and after treatment was 10.24 ± 3.11 vs. 13.16 ± 3.59 (P < 0.05), respectively; and RSI score before and after treatment was 15.82 ± 7.01 vs. 10.71 ± 6.64 (P < 0.05), respectively.

CONCLUSION:

The etiologies of most patients with RCC could be identified in the MDT clinic, and the cough-related symptoms of a significant number of patients with RCC improved in a short period.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Respir Investig Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Respir Investig Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos