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Prevalence of heart failure and trends in its pharmacological treatment between 2000 and 2017 among very old people.
Svahn, Sofia; Appelblad, Leona; Lövheim, Hugo; Gustafson, Yngve; Olofsson, Birgitta; Gustafsson, Maria.
Afiliación
  • Svahn S; Department of Medical and Translational Biology, Umeå University, Umeå, 901 87, Sweden. sofia.svahn@umu.se.
  • Appelblad L; Department of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, Umeå, 901 87, Sweden.
  • Lövheim H; Department of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, Umeå, 901 87, Sweden.
  • Gustafson Y; Department of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, Umeå, 901 87, Sweden.
  • Olofsson B; Department of Nursing, Umeå University, Umeå, 901 87, Sweden.
  • Gustafsson M; Department of Diagnostics and Intervention, Orthopedics, Umeå University, Umeå, 901 87, Sweden.
BMC Geriatr ; 24(1): 701, 2024 Aug 24.
Article en En | MEDLINE | ID: mdl-39182036
ABSTRACT

PURPOSE:

The aim of this study was to describe a population of very old people with heart failure (HF), to analyse the use of cardiovascular drugs over time, and to explore factors influencing cardiovascular drug treatment for this group.

METHODS:

All participants with information regarding HF diagnosis were selected from the Umeå 85+/Gerontological Regional Database (GERDA). The people in GERDA are all ≥85 years old. Trained investigators performed structured interviews and assessments. Information regarding medications and diagnoses was obtained from the participants and from medical records. Medical diagnoses were reviewed and confirmed by an experienced geriatrician.

RESULTS:

In this very old population, the prevalence of HF was 29.6% among women and 30.7% among men. Between 2000 and 2017, there was an increase in the use of renin-angiotensin (RAS) inhibitors (odds ratio [OR] 1.107, 95% confidence interval [CI] 1.072-1.144) and beta-blockers (BBs) (OR 1.123, 95% CI 1.086-1.161) among persons with HF, whereas the prevalence of loop diuretics (OR 0.899, 95% CI 0.868-0.931) and digitalis (OR 0.864, 95% CI 0.828-0.901) decreased (p < 0.001 for all drug classes). Higher age was associated with lower use of RAS inhibitors and BBs.

CONCLUSION:

In this HF population, the use of evidence-based medications for HF increased over time. This may be a sign of better awareness among prescribers regarding the under-prescribing of guidelines-recommended treatment to old people. Higher age associated with a lower prevalence of RAS inhibitors and BBs. This might indicate that further improvement is possible but could also represent a more cautious prescribing among frail very old individuals.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca Límite: Aged80 / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: BMC Geriatr Asunto de la revista: GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca Límite: Aged80 / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: BMC Geriatr Asunto de la revista: GERIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido