Durability of output-dependent QRS transition and left bundle branch capture in left bundle branch area pacing.
Heart Rhythm
; 2024 Aug 22.
Article
en En
| MEDLINE
| ID: mdl-39181484
ABSTRACT
BACKGROUND:
Although output-dependent QRS transition is a specific indicator that confirms left bundle branch (LBB) capture during left bundle branch area pacing (LBBAP), its durability remains unclear.OBJECTIVE:
The purpose of this study was to evaluate the presence of output-dependent QRS transition and capture thresholds of the LBB and left ventricular septal myocardium immediately and up to 1 year after the LBBAP procedure.METHODS:
We enrolled 129 patients with successful LBBAP who were available for 1-year follow-up postoperatively. Threshold testing was performed immediately after LBBAP on postoperative day 0 (POD-0) and after 3 days (POD-3), 6 months (POD-180), and 1 year (POD-360).RESULTS:
Output-dependent QRS transition persisted in 64 patients (88%) on POD-360, from among the 73 patients with output-dependent QRS transition on POD-0. In contrast, 55 of 56 patients without QRS transition on POD-0 (98%) did not exhibit QRS transition thereafter. LBB thresholds were slightly elevated on POD-360, albeit without statistical significance, compared with those on POD-0 (1.22 ± 1.00 V vs 1.43 ± 1.29 V at 0.4 ms; P = .26). The LBB thresholds increased by ≥1.5 V in 7 patients (11%). However, in 93% of patients with an LBB threshold of ≤2.5 V on POD-0, LBB capture was maintained at 2.5 V on POD-360. Left ventricular septal thresholds were similar on POD-0 and POD-360 (0.81 ± 0.36 V vs 0.83 ± 0.24 V; P = 1.0) and did not increase by ≥1.5 V in any patient.CONCLUSION:
Output-dependent QRS transitions were highly reproducible after implantation. Furthermore, LBB thresholds remained stable in most cases during the first postoperative year.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Heart Rhythm
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos