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Clinical characteristics and outcomes of Australian and Indian ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI).
Savage, M L; Hay, K; Sundar, H; Maharajan, R; Murdoch, D J; Latchumanadhas, K; Ezhilan, D M; Kalaichelvan, U; Denman, R; Ranasinghe, I; Subban, V; Walters, D L; Mullasari, A; Raffel, O C.
Afiliación
  • Savage ML; Cardiology Department, The Prince Charles Hospital, Brisbane, QLD, Australia; School of Clinical Medicine, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia. Electronic address: michael.savage@health.qld.gov.au.
  • Hay K; Cardiology Department, The Prince Charles Hospital, Brisbane, QLD, Australia; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
  • Sundar H; Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
  • Maharajan R; Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
  • Murdoch DJ; Cardiology Department, The Prince Charles Hospital, Brisbane, QLD, Australia; School of Clinical Medicine, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
  • Latchumanadhas K; Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
  • Ezhilan DM; Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
  • Kalaichelvan U; Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
  • Denman R; Cardiology Department, The Prince Charles Hospital, Brisbane, QLD, Australia; School of Clinical Medicine, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
  • Ranasinghe I; Cardiology Department, The Prince Charles Hospital, Brisbane, QLD, Australia; School of Clinical Medicine, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
  • Subban V; Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
  • Walters DL; Cardiology Department, The Prince Charles Hospital, Brisbane, QLD, Australia; School of Clinical Medicine, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
  • Mullasari A; Institute of Cardio Vascular Diseases, Madras Medical Mission, Chennai, India.
  • Raffel OC; Cardiology Department, The Prince Charles Hospital, Brisbane, QLD, Australia; School of Clinical Medicine, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
Indian Heart J ; 2024 Aug 22.
Article en En | MEDLINE | ID: mdl-39181445
ABSTRACT

INTRODUCTION:

The incidence of STEMI and subsequent mortality has been reported to be higher in Indian populations compared to developed countries. However, there is limited data directly comparing contemporary primary percutaneous coronary intervention (pPCI) treatment strategies and clinical outcomes for STEMI patients between developed and developing countries. MATERIALS AND

METHODS:

We compared population demographics, procedural characteristics, times to reperfusion and mortality in STEMI patients treated with pPCI between two tertiary referral centers in India and Australia respectively over a 3-year period (1st Jan 2017-31st Dec 2019).

RESULTS:

A total of 1293 STEMI presentations (896 Indian vs 397 Australian) were included. On average, Indian patients had lower median BMI than Australian patients (BMI 25.4 vs 27.8; p < 0.001), were significantly younger (mean age 56.0 vs 63.2 years; p < 0.001), more likely male (84 % vs 80 %; p = 0.046) and diabetic (48 % vs 18 %); p < 0.001). Radial access (50 % vs 88 %; p < 0.001) and TIMI III flow post PCI was also significantly lower (85 % vs 96 %; p < 0.001) with median door-to-balloon time significantly shorter in the Indian cohort (20mins vs 43mins; p < 0.001); however, median symptom to balloon time was significantly longer (245mins vs 160mins; p < 0.001). No significant differences in 30-day mortality (4.0 % vs 2.8 % Australian; p = 0.209) or 1-year mortality (6.5 % vs 4.3 %; p = 0.120) were observed.

CONCLUSION:

Significant differences in demographics and presentation characteristics exist between Indian and Australian STEMI patients treated with pPCI. Indian patients had significantly longer pre-hospital delays and lower achievement of TIMI III flow post PCI, yet shorter in-hospital time to treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian Heart J Año: 2024 Tipo del documento: Article Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian Heart J Año: 2024 Tipo del documento: Article Pais de publicación: India