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Vaccination status of patients with primary immunodeficiencies in Germany-a multicentric epidemiologic analysis.
Schwaneck, Eva C; Harasim, Anna S; Tony, Hans-Peter; Gawlik, Micha; Witte, Torsten; Joos, Stefanie; Gernert, Michael; Schmalzing, Marc; Morbach, Henner; Fröhlich, Matthias; Krone, Manuel.
Afiliación
  • Schwaneck EC; Division of Rheumatology/Immunology, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany. e.schwaneck@rheuma-hh.de.
  • Harasim AS; MVZ Rheumatologie und Autoimmunmedizin, Mönckebergstraße 27, 20095, Hamburg, Germany. e.schwaneck@rheuma-hh.de.
  • Tony HP; Division of Rheumatology/Immunology, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
  • Gawlik M; Division of Rheumatology/Immunology, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
  • Witte T; Department of Psychiatry and Psychotherapy, University of Würzburg, Margarete-Höppel-Platz 1, 97080, Würzburg, Germany.
  • Joos S; Helios Fachkliniken Hildburghausen, Hildburghausen, Deutschland.
  • Gernert M; Department of Rheumatology and Clinical Immunology, Hanover Medical School, Carl-Neuberg-Straße 1, 30625, Hanover, Germany.
  • Schmalzing M; Institute for General Practice and Interprofessional Healthcare, Eberhardt-Karls-University, Osianderstraße 5, 72076, Tübingen, Germany.
  • Morbach H; Division of Rheumatology/Immunology, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
  • Fröhlich M; Division of Rheumatology/Immunology, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
  • Krone M; Pediatric Immunology, Department of Pediatrics, University Hospital Würzburg, Josef-Schneider-Straße 2, 97080, Würzburg, Germany.
Z Rheumatol ; 2024 Aug 22.
Article en En | MEDLINE | ID: mdl-39174715
ABSTRACT

BACKGROUND:

Vaccinations represent an easily accessible, safe, and important method for preventing infections. Patients with primary immunodeficiencies (PID) are more susceptible to infections and should receive an extended spectrum of immunizations in many countries.

METHODS:

Between January 2019 and May 2020, vaccination certificates of 70 patients with PID from the regions of Würzburg and Hanover in Germany were evaluated. The patients were additionally surveyed regarding their attitude towards vaccinations and the communication with their physicians. Medical records were analyzed.

RESULTS:

Of the 70 patients, 54 (77%) suffered from common variable immunodeficiency, 30 (43%) were diagnosed with accompanying autoimmunity, 62 (89%) had an increased susceptibility to infections, and 56 (80%) were on immunoglobulin substitution therapy. Seven patients (10%) had neither a vaccination certificate nor were they able to recollect of their last vaccination. Only 55 (79%) and 43 (61%) patients stated that their rheumatologist or immunologist had recommended an influenza and a pneumococcal vaccination, respectively. When asked about their overall trust in vaccinations on a scale of 0 to 10 (0 = very low, 10 = very high), the mean value was 7.8. The most common vaccination was against tetanus in 63 (90%) patients, 49 (70%) had received vaccination against pneumococci, and 39 (56%) had received an influenza vaccination. Interestingly, 26 patients (37%) were vaccinated against measles, even though this is contraindicated in most PID patients.

CONCLUSION:

Our data suggest that vaccination rates in this at-risk population are insufficient. Healthcare providers should emphasize vaccinations routinely when caring for these patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Z Rheumatol Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Z Rheumatol Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania