Obstetric antiphospholipid syndrome.

Soto-Peleteiro, Adriana; Gonzalez-Echavarri, Cristina; Ruiz-Irastorza, Guillermo

Soto-Peleteiro, Adriana; Gonzalez-Echavarri, Cristina; Ruiz-Irastorza, Guillermo.

Afiliación

Soto-Peleteiro A; Autoimmune Diseases Research Unit, Department of Internal Medicine, Biobizkaia Health Research Institute, Hospital Universitario Cruces, Spain.
Gonzalez-Echavarri C; Autoimmune Diseases Research Unit, Department of Internal Medicine, Biobizkaia Health Research Institute, Hospital Universitario Cruces, Spain.
Ruiz-Irastorza G; Autoimmune Diseases Research Unit, Department of Internal Medicine, Biobizkaia Health Research Institute, Hospital Universitario Cruces, Spain; University of The Basque Country, Bizkaia, The Basque Country, Spain. Electronic address: r.irastorza@outlook.es.

Med Clin (Barc) ; 163 Suppl 1: S14-S21, 2024 08.

Article en En, Es | MEDLINE | ID: mdl-39174149

ABSTRACT

ABSTRACT

Antiphospholipid syndrome (APS) is the most frequent acquired thrombophilia of autoimmune basis. Pregnancy complications of APS may include recurrent miscarriage, and placental dysfunction presenting as fetal death, prematurity, intrauterine growth restriction and preeclampsia. For the management of obstetric APS, a coordinated medical-obstetric management is essential, and this should start for a preconceptional visit in order to estimate the individual risk for complications, adjust therapies and establish the indications for preconceptional and first-trimester therapy. The basis of APS therapy during pregnancy is low-dose aspirin, combined in certain clinical scenarios with low-molecular weight heparin. Induction of delivery should not be routinely indicated in the absence of maternal and/or fetal complications. Postpartum management should be warranted.

Asunto(s)

Síndrome Antifosfolípido; Síndrome Antifosfolípido/complicaciones; Síndrome Antifosfolípido/diagnóstico; Humanos; Embarazo; Femenino; Aspirina/uso terapéutico; Complicaciones del Embarazo/terapia; Complicaciones del Embarazo/diagnóstico; Anticoagulantes/uso terapéutico; Heparina de Bajo-Peso-Molecular/uso terapéutico; Complicaciones Hematológicas del Embarazo/diagnóstico; Complicaciones Hematológicas del Embarazo/terapia

Palabras clave

Aborto; Anticardiolipin; Anticardiolipina; Anticoagulante lúpico; Anticuerpos antifosfolípido; Antiphospholipid antibodies; Aspirina; Fetal loss; Heparin; Heparina; Hidroxicloroquina; Hydroxychloroquine; Low-dose aspirin; Lupus anticoagulant; Miscarriage; Muerte fetal; Preeclampsia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome Antifosfolípido Límite: Female / Humans / Pregnancy Idioma: En / Es Revista: Med Clin (Barc) Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: España

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