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[Mycotoxin intoxication in 54 dogs after ingestion of walnuts]. / Mykotoxinvergiftung nach Walnussaufnahme bei 54 Hunden.
Braun, Vanessa; Kanstinger, Alina; Dahlem, Dorothee.
Afiliación
  • Braun V; Abteilung Innere Medizin, Kleintierklinik Ettlingen, Tierärztliche Klinik für Chirurgie, Praxis für Kleintiere, Ettlingen.
  • Kanstinger A; Abteilung Innere Medizin, Kleintierklinik Ettlingen, Tierärztliche Klinik für Chirurgie, Praxis für Kleintiere, Ettlingen.
  • Dahlem D; Abteilung Innere Medizin, Kleintierklinik Ettlingen, Tierärztliche Klinik für Chirurgie, Praxis für Kleintiere, Ettlingen.
Article en De | MEDLINE | ID: mdl-39173649
ABSTRACT

OBJECTIVE:

The aim of this retrospective study was to decribe the intoxication with tremorgenic mycotoxins subsequent to the ingestion of walnuts in a large population of dogs and the evaluation of the development of the clinical signs under the initiated treatment. MATERIAL AND

METHODS:

The study included 54 dogs exhibiting signs of tremor, hyperesthesia, hyperthermia and ataxia, in particular a few hours following observed ingestion of walnuts or its justified suspicion.

RESULTS:

The patients were presented to the clinic mostly during winter and spring. Fifty-three of 54 dogs were hospitalized for symptomatic, decontaminating and eliminating therapy (98%). Symptomatic treatment comprised of anticonvulsant therapy in 14 dogs (26%) and an antiemetic therapy in for half of the patients (n=27; 50%). A forced emesis for decontamination was undertaken in only 6 patients due to the severity of their neurological symptoms (11%). For further decontamination, an oral administration of activated charcoal after improvement of clinical signs (n=39; 72%). The majority of dogs (n=45; 83%) additionally received an intravenous lipid therapy for toxin elimination and isotonic crystalloid solution to compensate fluid losses. There were no side effects observed following the administration of intravenous lipid therapy. The majority of dogs were hospitalized for a duration of 2 days (n=44; 81%). In most dogs, examination was unremarkable on the day of their release (n=39; 72%). Potential long-term sequelae of the intoxication were not recorded in any patient.

CONCLUSION:

Due to the lipophilic nature of mycotoxins, the use of intravenous lipid therapy may considered for toxin elimination purposes. The prognosis of mycotoxin intoxication following walnut ingestion is good with decontamination and elimination measures. CLINICAL RELEVANCE In the case of unspecific neurological signs such as tremor, ataxia and hyperesthesia as well as a corresponding preliminary report, an intoxication with mycotoxin-containing walnuts should be considered.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Juglans / Enfermedades de los Perros / Micotoxinas Límite: Animals Idioma: De Revista: Tierarztl Prax Ausg K Kleintiere Heimtiere Asunto de la revista: MEDICINA VETERINARIA Año: 2024 Tipo del documento: Article Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Juglans / Enfermedades de los Perros / Micotoxinas Límite: Animals Idioma: De Revista: Tierarztl Prax Ausg K Kleintiere Heimtiere Asunto de la revista: MEDICINA VETERINARIA Año: 2024 Tipo del documento: Article Pais de publicación: Alemania