Your browser doesn't support javascript.
loading
Apigenin ameliorates petrol vapors-induced oxidative stress as occupational and environmental pollutants in rats: An in vivo study.
Ghahri, Asghar; Saboji, Mojdeh; Hatami, Hosna; Ranjbar, Amir; Salimi, Ahmad; Seydi, Enayatollah.
Afiliación
  • Ghahri A; Department of Occupational Health and Safety Engineering, School of Health, Alborz University of Medical Sciences, Karaj, Iran.
  • Saboji M; Research Center for Health, Safety and Environment, Alborz University of Medical Sciences, Karaj, Iran.
  • Hatami H; Department of Biology, Plant Physiology, Faculty of Science, Payame Noor University, Tehran, Iran.
  • Ranjbar A; Department of Occupational Health and Safety Engineering, School of Health, Alborz University of Medical Sciences, Karaj, Iran.
  • Salimi A; Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran.
  • Seydi E; Department of Occupational Health and Safety Engineering, School of Health, Alborz University of Medical Sciences, Karaj, Iran.
Arch Environ Occup Health ; 79(3-4): 143-151, 2024.
Article en En | MEDLINE | ID: mdl-39169800
ABSTRACT
Petrol vapors as important occupational and environmental pollutants can cause oxidative stress and may play a role in the development of neurodegenerative diseases along with the risk factors involved. This research is designed as a preliminary study to evaluate the protective effects of apigenin (APG) on oxidative stress caused by petrol vapors inhalation in rats. A total of 24 male Wistar rats were randomly divided into four groups inside the inhalation chamber. Body weight changes and oxidative stress markers were investigated. The average body weight of the group exposed to petrol vapors was significantly lower compared to the other groups. The level of reactive oxygen species (ROS), content of oxidized-glutathione (GSSG), and Malondialdehyde were found to be higher in the petrol-inhaled group, while the content of reduced-glutathione (GSH) was lower compared to the other groups. APG administration did result in any significant improvement in these toxicities induced by petrol vapor. APG administration may ameliorate the petrol-induced oxidative stress. In chronic exposures, in addition to personal protection and engineering control, the use of compounds of natural origin may help in reducing the side effects (such as CNS) caused by exposure to petrol vapors.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Ratas Wistar / Estrés Oxidativo / Apigenina Límite: Animals Idioma: En Revista: Arch Environ Occup Health Asunto de la revista: MEDICINA OCUPACIONAL / SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Ratas Wistar / Estrés Oxidativo / Apigenina Límite: Animals Idioma: En Revista: Arch Environ Occup Health Asunto de la revista: MEDICINA OCUPACIONAL / SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos