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Efficacy and safety of self-expandable metallic stents for management of benign gastric outlet obstruction-A prospective study.
Singh, Alok Kumar; Krishnapriya, V; Sachdeva, Sanjeev; Puri, Amarender S; Kumar, Ajay; Sonika, Ujjwal; Srivastava, Siddharth; Dalal, Ashok.
Afiliación
  • Singh AK; Department of Gastroenterology, G.B. Pant Hospital, Room No. 210, Academic Block, J L N Marg, New Delhi, 110 002, India.
  • Krishnapriya V; Department of Gastroenterology, G.B. Pant Hospital, Room No. 210, Academic Block, J L N Marg, New Delhi, 110 002, India.
  • Sachdeva S; Department of Gastroenterology, G.B. Pant Hospital, Room No. 210, Academic Block, J L N Marg, New Delhi, 110 002, India.
  • Puri AS; Department of Gastroenterology, Medanta-The Medicity Hospital, Gurugram, 122 001, India.
  • Kumar A; Department of Gastroenterology, G.B. Pant Hospital, Room No. 210, Academic Block, J L N Marg, New Delhi, 110 002, India.
  • Sonika U; Department of Gastroenterology, G.B. Pant Hospital, Room No. 210, Academic Block, J L N Marg, New Delhi, 110 002, India.
  • Srivastava S; Department of Gastroenterology, G.B. Pant Hospital, Room No. 210, Academic Block, J L N Marg, New Delhi, 110 002, India.
  • Dalal A; Department of Gastroenterology, G.B. Pant Hospital, Room No. 210, Academic Block, J L N Marg, New Delhi, 110 002, India. drashokdalal83@gmail.com.
Indian J Gastroenterol ; 43(5): 1030-1036, 2024 Oct.
Article en En | MEDLINE | ID: mdl-39167299
ABSTRACT

INTRODUCTION:

We aimed at evaluating the safety and efficacy of self-expandable metallic stent (SEMS) insertion for managing patients with benign gastric outlet obstruction (GOO).

METHODS:

This prospective interventional study included 23 patients. All consecutive treatment-naïve symptomatic patients with benign GOO were recruited. Fully covered SEMS were deployed across the stricture under fluoroscopic and endoscopic guidance. Technical success, clinical success and sustained treatment response (STR) were assessed. Technical success was defined as the successful deployment of SEMS at the desired anatomic location. Clinical success was defined as the resolution of symptoms and an increase in Gastric Outlet Obstruction Scoring System (GOOSS) of at least 1 point from the baseline score on Day 7. STR was assessed at four and eight weeks post stent removal in patients who had a response at week four. Factors associated with stent migration and non-response at week four were also assessed.

RESULTS:

The median age of the study population was 30 years (range 19-65 years). Males constituted 65.22%. Most patients presented with vomiting (100%) and abdominal pain (95.65%). Peptic stricture was most common etiology for GOO (60.9%) followed by tubercular (26.1%) and corrosive (13%). Most common site of obstruction was junction of first and second part of duodenum (69.57%) followed by pyloric (30.43%). Median length of stricture was 2 cm (range 1.5-4). Technical success was achieved in all 23 patients (100%). Clinical success was achieved in 21 patients (91.3%). Response at Day 28 was seen in 20 patients (86.95%). Eighteen of 20 (90%) patients who had a response at week four had STR at week four and week eight after stent removal. Stent migration occurred in five (21.7%) patients. On univariate analysis, stricture length, calibre and stent length were found to predict migration.

CONCLUSIONS:

Fully covered SEMS was an effective and safe management modality in patients with benign GOO. Stent migration remains a troublesome disadvantage.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción de la Salida Gástrica / Stents Metálicos Autoexpandibles Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Indian J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción de la Salida Gástrica / Stents Metálicos Autoexpandibles Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Indian J Gastroenterol Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India