Your browser doesn't support javascript.
loading
Intra-Ethnic and Geographic Disparities in Stage at Diagnosis for Non-Small Cell Lung Cancer.
Liu, Qinran; Medina, Heidy N; Koru-Sengul, Tulay; Rodriguez, Estelamari; Lopes, Gilberto; Penedo, Frank J; Islami, Farhad; Pinheiro, Paulo S.
Afiliación
  • Liu Q; Surveillance & Health Equity Science Department, American Cancer Society, Atlanta, GA, USA.
  • Medina HN; Department of Public Health Sciences, University of Miami School of Medicine, Miami, FL, USA.
  • Koru-Sengul T; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
  • Rodriguez E; Department of Public Health Sciences, University of Miami School of Medicine, Miami, FL, USA.
  • Lopes G; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
  • Penedo FJ; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
  • Islami F; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
  • Pinheiro PS; Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
J Natl Cancer Inst ; 2024 Aug 21.
Article en En | MEDLINE | ID: mdl-39167098
ABSTRACT

BACKGROUND:

Despite the importance of early detection for lung cancer outcomes, staging disparities among the growing US Hispanic population remain underexplored. This population-based study aimed to identify racial-ethnic disparities among non-Hispanic White, non-Hispanic Black, and Hispanic (including specific subgroups) patients in stage at diagnosis for potentially curable non-small cell lung cancer (NSCLC).

METHODS:

Incident NSCLC cases (2005-2018) were extracted from the Florida cancer registry. Stage was categorized as early (localized/regional) or advanced (distant). Multivariable logistic regression assessed the association between race/ethnicity and stage at diagnosis, adjusting for socioeconomic status, smoking, and clinical factors.

RESULTS:

Among 157,034 NSCLC patients, 47.8% were diagnosed at an advanced-stage. Multivariable models showed higher odds of advanced-stage diagnosis for non-Hispanic Blacks (ORadj=1.22; 95%CI 1.17-1.26) and Hispanics (ORadj=1.03; 95%CI 1.00-1.08) compared to non-Hispanic Whites. Regional differences were stark for Hispanics compared to non-Hispanic Whites ORadj 0.96 (95%CI 0.91-1.01) in South Florida vs 1.12 (95%CI 1.05-1.19) in the rest of Florida. In South Florida, Central Americans (ORadj=1.49; 95%CI 1.20-1.85) were the only Hispanic group showing a staging disadvantage compared to non-Hispanic Whites.

CONCLUSION:

Pronounced disparities in NSCLC staging among non-Hispanic Black and Hispanic populations, with notable regional variations within Florida's Hispanic communities, indicate that targeted interventions could significantly enhance early detection. The relative advantage observed in nearly all minority groups in multicultural South Florida compared to the rest of Florida underscores the need for future research exploring how specific Hispanic and multiracial sociocultural contexts can positively influence the landscape of cancer early detection across the US.
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Natl Cancer Inst Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Natl Cancer Inst Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos