Your browser doesn't support javascript.
loading
Peripheral liver metastases are more frequently missed than central metastases in contrast-enhanced CT: insights from a 25-reader performance study.
Hsieh, Scott S; Holmes Iii, David R; Carter, Rickey E; Tan, Nelly; Inoue, Akitoshi; Yalon, Mariana; Gong, Hao; Sudhir Pillai, Parvathy; Leng, Shuai; Yu, Lifeng; Fidler, Jeff L; Cook, David A; McCollough, Cynthia H; Fletcher, Joel G.
Afiliación
  • Hsieh SS; Mayo Clinic, Rochester, USA. Hsieh.Scott@mayo.edu.
  • Holmes Iii DR; Mayo Clinic, Rochester, USA.
  • Carter RE; Mayo Clinic, Rochester, USA.
  • Tan N; Mayo Clinic, Rochester, USA.
  • Inoue A; Mayo Clinic, Rochester, USA.
  • Yalon M; Shiga University of Medical Science, Otsu, Japan.
  • Gong H; Mayo Clinic, Rochester, USA.
  • Sudhir Pillai P; Mayo Clinic, Rochester, USA.
  • Leng S; Mayo Clinic, Rochester, USA.
  • Yu L; The University of Texas MD Anderson Cancer Center, Houston, USA.
  • Fidler JL; Mayo Clinic, Rochester, USA.
  • Cook DA; Mayo Clinic, Rochester, USA.
  • McCollough CH; Mayo Clinic, Rochester, USA.
  • Fletcher JG; Mayo Clinic, Rochester, USA.
Abdom Radiol (NY) ; 2024 Aug 20.
Article en En | MEDLINE | ID: mdl-39162799
ABSTRACT

PURPOSE:

Subtle liver metastases may be missed in contrast enhanced CT imaging. We determined the impact of lesion location and conspicuity on metastasis detection using data from a prior reader study.

METHODS:

In the prior reader study, 25 radiologists examined 40 CT exams each and circumscribed all suspected hepatic metastases. CT exams were chosen to include a total of 91 visually challenging metastases. The detectability of a metastasis was defined as the fraction of radiologists that circumscribed it. A conspicuity index was calculated for each metastasis by multiplying metastasis diameter with its contrast, defined as the difference between the average of a circular region within the metastasis and the average of the surrounding circular region of liver parenchyma. The effects of distance from liver edge and of conspicuity index on metastasis detectability were measured using multivariable linear regression.

RESULTS:

The median metastasis was 1.4 cm from the edge (interquartile range [IQR], 0.9-2.1 cm). Its diameter was 1.2 cm (IQR, 0.9-1.8 cm), and its contrast was 38 HU (IQR, 23-68 HU). An increase of one standard deviation in conspicuity index was associated with a 6.9% increase in detectability (p = 0.008), whereas an increase of one standard deviation in distance from the liver edge was associated with a 5.5% increase in detectability (p = 0.03).

CONCLUSION:

Peripheral liver metastases were missed more frequently than central liver metastases, with this effect depending on metastasis size and contrast.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Abdom Radiol (NY) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Abdom Radiol (NY) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos