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Exploring the Challenges of Recruiting Older People for a Randomised Trial Assessing the Feasibility of Treating White Coat Hypertension in the UK General Practices: A Mixed-methods study.
Mensah, Ekow; Ali, Khalid; Okorie, Michael; Bremner, Stephen; McAlister, Colin; Perry, Nicky; Rajkumar, Chakravarthi.
Afiliación
  • Mensah E; Department of Medicine, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.
  • Ali K; University Hospitals Sussex NHS Foundation Trust, Brighton-United Kingdom.
  • Okorie M; Department of Medicine, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.
  • Bremner S; University Hospitals Sussex NHS Foundation Trust, Brighton-United Kingdom.
  • McAlister C; Department of Medicine, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom.
  • Perry N; University Hospitals Sussex NHS Foundation Trust, Brighton-United Kingdom.
  • Rajkumar C; Department of Statistics, University of Sussex, Brighton-United Kingdom.
Curr Hypertens Rev ; 2024 Aug 19.
Article en En | MEDLINE | ID: mdl-39162278
ABSTRACT

INTRODUCTION:

There is a recognised association between white coat hypertension (WCH) and adverse cardiovascular outcomes in older adults. However, there is no consensus on the management of WCH in this group. The objective of the Hypertension in the Very Elderly Trial (HYVET-2) study was to assess the feasibility of randomising 100 patients > 75years with WCH from General Practice in the UK to treatment or usual care. The study did not randomise any patients. In this follow-up study, we sought to explore the reasons for not recruiting.

METHODS:

Furthermore, using a mixed-methods study design, staff from 29 General Practice (GP) sites and the Clinical Research Network (CRN) in Kent, Surrey, and Sussex (KSS), UK, were sent an online questionnaire about local research facilities and infrastructure, and HYVET-2 study methodology and target population demographics.

RESULTS:

Nineteen (19) individuals responded to the online questionnaires (15 primary care staff, 4 CRN staff). Moreover, using a framework approach, we identified six themes summarising challenges to HYVET-2 recruitment. These themes are established approaches of primary care towards managing WCH in older people, target patient demographics, study design complexity, patient- facing study documents, limited research resources in primary care, and identification of eligible patients using existing coding.

CONCLUSION:

Our experience showed that recruiting older people from primary care to a WCH study was not feasible. A national scoping survey amongst primary care physicians in the UK, as well as robust patient and public involvement (PPI) targeting older people with WCH, might improve recruitment in future studies addressing the management of WCH in older people.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Curr Hypertens Rev Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Emiratos Árabes Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Curr Hypertens Rev Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Emiratos Árabes Unidos