Your browser doesn't support javascript.
loading
Test-retest and interrater reliability of experimental within-subject variability of pain reports as assessed by the focused analgesia selection test.
Agostinho, Mariana; Shani, Adi; Canaipa, Rita; Treister, Roi.
Afiliación
  • Agostinho M; The Cheryl Spencer Department of Nursing, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.
  • Shani A; CIIS, Centre for Interdisciplinary Health Research, Faculty of Health Sciences and Nursing, Universidade Católica Portuguesa, Lisbon, Portugal.
  • Canaipa R; The Cheryl Spencer Department of Nursing, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.
  • Treister R; Department of Orthopedics B and Spine Surgery, Galilee Medical Centre, Nahariya, Israel.
Pain Rep ; 9(5): e1175, 2024 Oct.
Article en En | MEDLINE | ID: mdl-39161417
ABSTRACT

Introduction:

Within-subject variability (WSV) of pain intensity reports has been shown to predict the placebo response. The focused analgesia selection test (FAST), which allows to experimentally assess WSV of pain reports, has been used as a screening tool to identify participants who are likely to have a strong placebo response in drug-development clinical trials. Yet, the reliability of FAST has not been reported.

Objectives:

To assess test-retest and interrater reliability of the FAST outcomes. To mimic pharma-sponsored clinical trials, we enlisted inexperienced assessors who underwent limited training.

Methods:

Healthy volunteers performed the FAST twice within a week and were randomly assigned to either the test-retest group or the interrater group. T-tests, partial Pearson correlations, intraclass correlations (ICC), and Bland-Altman plots were generated to assess FAST outcomes' reliability.

Results:

Sixty-three participants completed the study and were assigned to the test-retest (N = 33) or interrater (N = 30) arms. No statistically significant differences in the FAST outcomes were detected between the 2 sessions, except for the FAST covariance (FAST CoV) in the interrater assessment (P = 0.009). Test-retest reliabilities of the FAST-main outcomes were r = 0.461, ICC = 0.385 for the FAST R 2 and r = 0.605, ICC = 0.539 for the FAST ICC and in the interrater cohort, they were FAST R 2 r = 0.321, ICC = 0.337 and FAST ICC r = 0.355, ICC = 0.330.

Conclusion:

Using inexperienced assessors, the FAST outcomes test-retest ranged from moderate to strong, whereas the interrater reliability ranged from weak to poor. These results highlight the importance of adequately training study staff members before using this tool in multicentre clinical trials.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pain Rep Año: 2024 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pain Rep Año: 2024 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Estados Unidos